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Foot and Ankle Fracture Healing – vitamin D appears promising for everyone– review May 2015

Vitamin D in Foot and Ankle Fracture Healing: A Literature Review and Research Design.

Foot Ankle Spec. 2015 May 11. pii: 1938640015585958. [Epub ahead of print]
Bernhard A1, Matuk J2.

Vitamin D is a generic name for a group of essential vitamins, or secosteroids, important in calcium homeostasis and bone metabolism. Specifically, efficacy of vitamin D with regard to bone healing is in question. A literature review was performed, finding mostly large studies involving vitamin D effects on prevention of fractures and randomized animal model studies consisting of controlled fractures with vitamin D interventions. The prevention articles generally focus on at-risk populations, including menopausal women and osteoporotic patients, and also most often include calcium in the treatment group. Few studies look at vitamin D specifically. The animal model studies often focus more on vitamin D supplementation; however the results are still largely inconclusive. While recent case reports appear promising, the ambiguity of results on the topic of fracture healing suggests a need for more, higher level research. A novel study design is proposed to help determine the efficacy on vitamin D in fracture healing.

LEVELS OF EVIDENCE:
Therapeutic Level IV: Systematic Review.

PMID: 25964289


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Vitamin D, Vitamin K2, and Magneium will probably prevent Foot and Ankle Fracture

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Attached files

ID Name Comment Uploaded Size Downloads
5941 Foot T1C.jpg admin 19 Sep, 2015 94.31 Kb 20947
5940 Foot T1B.jpg admin 19 Sep, 2015 111.91 Kb 1675
5939 Foot T1A.jpg admin 19 Sep, 2015 126.13 Kb 3176
5938 Vitamin D in Foot and Ankle.pdf admin 19 Sep, 2015 500.68 Kb 2667