Vitamin D and Obesity: Two Interacting Players in the Field of Infertility.
Nutrients. 2019 Jun 27;11(7). pii: E1455. doi: 10.3390/nu11071455.
Bosdou JK1, Konstantinidou E2, Anagnostis P3, Kolibianakis EM1, Goulis DG2.
- Vitamin D is needed for human fertility – goal is 50 ng – Sept 2018
- Poor fertility in both women and men associated with low vitamin D – review Feb 2018
- Infertility - 71 percent of the time of BOTH partners had less than 20 ng of Vitamin D – Aug 2017
Items in both categories Obesity and Fertility are listed here:
Items in both of the categories Intervention AND Fertility/Sperm
- In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024
- Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT Aug 2020
- Women had better sexual desire, orgasm and satisfaction after Vitamin D supplementation – Feb 2018
- Testosterone and erectile function increased after vitamin D supplementation – Jan 2018
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Increased Testosterone and Erectile function, decreased weight with Vitamin D – March 2017
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
Fertility and Sperm category contains the following summary
See also:
Overview Women and Vitamin D
Overview Pregnancy and vitamin D Fertility and Vitamin D – several articles
Endometriosis
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" in 11 VitaminDWiki titles as of Jan 2022
Search VitaminDWiki for "Assisted reproduction" 177 items as of Sept 2019
Search VitaminDWiki for "polycystic ovary syndrome" OR PCOS" Sept 2019
Search VitaminDWiki fore Testosterone 77 items just in webpages as of Sept 2020
Search VitaminDWiki for "erectile dysfunction" 120 items as of July 2018
Conception and vitamin D snapshot as of 2012
Download the PDF from VitaminDWiki
(This article belongs to the Special Issue Vitamin D and Obesity)
Obesity plays an important role in human fertility in both genders.
The same is true for vitamin D, for which accumulating evidence from observational human studies suggests a key role for both male and female fertility. In the latter case, however, robust data from relevant interventional studies are currently lacking.
It is also not clear whether obesity and vitamin D deficiency, besides their independent effect on human infertility, act in synergy.
Several pathogenetic mechanisms may be proposed as a linkage between vitamin D deficiency and obesity, with respect to infertility. In any case, the independent contribution of vitamin D deficiency in obese infertile states needs to be proven in interventional studies focusing on either vitamin D supplementation in obese or weight loss strategies in vitamin D-deficient infertile patients.
Table 1. Vitamin D and infertility
Male infertility
Linear or U-shaped correlation between vitamin D concentrations and sperm motility/morphology
Sufficient vitamin D concentrations associated with high testosterone concentrations
Supplementation of vitamin D improved semen quality and pregnancy rates
Supplementation of vitamin D increased testosterone concentrations
Female infertility
Contradictory data on whether supplementation of vitamin D is associated with pregnancy rates
ART (assisted reproductive techniques)
Higher live birth rates in vitamin D-sufficient women
Endometriosis
Linear correlation between vitamin D concentrations and diameter of ovarian endometriomas
Higher incidence of vitamin D deficiency/insufficiency in women with endometriosis
PCOS (polycystic ovary syndrome)
Linear correlation between vitamin D levels and reproductive success rates after ovulation induction in women with PCOS
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