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Curcumin

16 items in Curcumin category - see also Supplements
Did you know?
  • Curcumin increases amount of Vitamin D in blood which actually gets to the tissue
  • Curcumin is a naturally-occurring chemical compound found in the spice turmeric.
  • Curcumin bioavailability varies 100X between types
    • When taken separately from food - apparently not nearly as much if taken with a meal
  • Vitamin D Receptor Activation can be increased by any of: Resveratrol,  Omega-3,  Magnesium, Zinc Quercetin,  non-daily Vit D.  Curcumin, intense exercise,  Ginger,  Essential oils, etc   Note: The founder of VitaminDWiki uses 10 of the 12 known VDR activators
    • (More Curcumin info below this box)

Learn how Vitamin D is essential for good health
  Watch a 5 minute video "Does Less Sun Mean more Disease?"
  Browse for other Health Problems and D in left column or here
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If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Proof that Vitamin D Works   Getting Vitamin D into your body

Is 50ng enough?   How to restore levels quickly  VitaminDWiki interview and transcript - Lahore Jan 2022
Books and Videos 273   Diseases that may be related via low vitamin D
Reasons for low response to vitamin D   Why are doctors reluctant
Cancer studies include:   Breast 259   Colon 144   Lung 55   Prostate 103   Pancreatic 58   Skin 121
Colds and flu   Dark Skin 467   Diabetes 551   Obesity 442   Pregnancy 920   Seniors 430
COVID-19 treated by Vitamin D - studies, reports, videos


Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment - March 2024

Table of Contents
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 Download the PDF from VitaminDWiki


Curcumin fights many health problems when it is more bio-available – June 2023

Pharmacological Mechanisms and Clinical Applications of Curcumin: Update
Aging Dis. 2023 Jun 1;14(3):716-749. doi: 10.14336/AD.2022.1101.
Min Hao 1, Yue Chu 1, Jingxuan Lei 1 2, Zhouhui Yao 1, Pingping Wang 1, Ziyan Chen 1, Kuilong Wang 1, Xianan Sang 1, Xin Han 1, Lu Wang 1, Gang Cao 1

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Curcumin, a well-known hydrophobic polyphenol extracted from the rhizomes of turmeric (Curcuma longa L.), has attracted great interest in the last ten years due to its multiple pharmacological activities. A growing body of evidence has manifested that curcumin has extensive pharmacological activities including anti-inflammatory, anti-oxygenation, lipid regulation, antiviral, and anticancer with hypotoxicity and minor adverse reactions. However, the disadvantages of low bioavailability, short half-life in plasma, low drug concentration in blood, and poor oral absorption severely limited the clinical application of curcumin. Pharmaceutical researchers have carried out plenty of dosage form transformations to improve the druggability of curcumin and have achieved remarkable results. Therefore, the objective of this review summarizes the pharmacological research progress, problems in clinical application and the improvement methods of curcumin's druggability. By reviewing the latest research progress of curcumin, we believe that curcumin has a broad clinical application prospect for its wide range of pharmacological activities with few side effects. The deficiencies of lower bioavailability of curcumin could be improved by dosage form transformation. However, curcumin in the clinical application still requires further study regarding the underlying mechanism and clinical trial verification.
 Download the PDF from VitaminDWiki

Some of the Health Problems fought by Curcumin (are also fought by Vitamin D)

Overweight and obesity
Metabolic syndrome
Nonalcoholic fatty liver disease
Depression and anxiety in diabetic patients with peripheral neuropathy
Type 2 diabetes
Alzheimer disease
Schizophrenia
Prostate cancer
Cancer
Polycystic ovary- syndrome
Non-Alcoholic Fatty Liver Disease (NAFLD)


Curcumin benefits - 2020

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  • Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications - 2020 PDF

16 Curcumin articles


Tumeric-Curcumin products review - June 2023 Consumerlab

Consumerlab has a free trial subscription 100+ supplement reviews
58 page review includes effectivness studies, bio-availablity studies ( up to 185X), high-dose toxicity, cost, etc
   see Excellent reviews of supplements at ConsumerLab


When not to take curcumin - 2018

Turmeric: potential adverse effects and interactions_

  • Turmeric and curcumin seem to be generally well tolerated. The most common side effects observed in clinical studies are gastrointestinal and include constipation, dyspepsia, diarrhoea, distension, gastroesophageal reflux, nausea, vomiting, yellow stool and stomach ache.
  • Due to their ability to increase bile secretion, turmeric and curcumin should not be taken by individuals with obstruction of the bile duct, cholangitis, liver disease, gallstones and any other biliary disease.
  • Turmeric has also been linked to interactions with some conventional medicines due to its influence on some cytochrome P450 enzymes, P-glycoprotein and OATP transporters.
  • Patient’s taking medicines with a narrow therapeutic index or, associated with significant side effects, e.g. anticancer or immunosuppressant agents should use turmeric and curcumin with caution.

Piperine (pepper) added to Curcumin makes it 20X more bioavailable

Turmeric with Black Pepper: What It’s Good For and How to Take It Dr, Greger video April 2022

  • "Approximately 5 percent of the spice turmeric is composed of an active compound called curcumin, which is responsible for turmeric’s bright yellow color."
  • "About 5 percent of black pepper by weight is comprised of piperine, a compound that gives the spice its pungent flavor. Piperine is a potent inhibitor of drug metabolism. One of the ways our liver gets rid of foreign substances is by making them water soluble so they can be more easily excreted. But, this black pepper molecule inhibits that process."
  • "And guess what a common ingredient in curry powder is besides turmeric? Black pepper."

GreenMedInfo


900 Reasons Turmeric May Be the World's Most Important Herb - April 2023

GreenMedInfo


Curcumin was associated with Omega-3 7, Supplement 4, Zinc 4, Resveratrol 4, Magnesium 3, Vitamin K 3, Boron 3, Iodine 3, Vitamin B12 3, Vitamin C 3

as of July 2024 - click for details


Created by admin. Last Modification: Tuesday July 30, 2024 15:02:19 GMT-0000 by admin. (Version 32)

Attached files

ID Name Comment Uploaded Size Downloads
21479 Curcumin forms 2.webp admin 30 Jul, 2024 24.77 Kb 23
21478 Curcumin ToC.webp admin 30 Jul, 2024 24.99 Kb 38
21476 Enhancing the Bioavailability and Bioactivity of Curcumin_CompressPdf.pdf admin 30 Jul, 2024 386.85 Kb 32
21474 Curcumin forms.webp admin 30 Jul, 2024 32.42 Kb 27
21473 Curcumin action.webp admin 30 Jul, 2024 39.14 Kb 23
21472 Health uses of Curcumin_CompressPdf.pdf admin 30 Jul, 2024 675.80 Kb 40
17825 Turmeric and Its Major Compound Curcumin on Health_CompressPdf.pdf admin 11 Jun, 2022 605.21 Kb 1948
17824 Curcumin circles.jpg admin 11 Jun, 2022 26.47 Kb 381