CLICK HERE for Updates for 2012
Several sections to this web page
Followed by links to previous US Vitamin D Clinical Trials pages
Very difficult for a doctor to keep up 75 trials and 11 systematic reviews published every day – Sept 2010
US March 2011
Examples from over 672 intervention clinical trials
- see blood response for up to 5,000 IU of vitamin D
- Effect of vitamin D on menopause symptoms kaiser
- Colorectal Cancer 50,000 IU 3 per week till repleted
- Primary Hyperparathyroidism 50,000 IU
- Meal: no meal, high fat meal, low fat meal 50,000 IU once a month
- 2000 IU during pregnancy and bone status of infant hint - should have >4,000 IU
- Colorectal Cancer - try to achieve 40 to 50 ng/ml
- Obesity 4,000 IU daily
- Hypertension 4,000 IU daily
- Pregnancy 2,800 IU daily
- Treat Pruritis in Hemodialysis Patients 50,000 IU D2 weekly
- Nocturnal Leg Cramps 50,000 IU D2 daily
- Kidney Transplant 50,000 IU weekly
- Treatment of Vitamin D Insufficiency loading dose of 50,000 IU daily
- - - - - - - - - - - - - - - - - - - - - - - - - - - - -
A few high dose vitamin D intervention Clinical Trials - update Aug 2011
- Bone loss after breast cancer - 50,000 IU weekly
- Male fertility - 300,000 IU followed by 1,400 IU daily
- Immune Function 5,000 IU daily
- Sickle Cell Disease up to 600,000 IU one time
- congestive heart failure4,000 IU daily
- Falls 100,000 IU monthly
- Sleep Apnea 400,000 IU one time
- Reduce progress of Alzheimer's 100,000 IU monthly
- Parkinson's slowed with 7,400 IU daily
- Parkinson's slowed with 10,000 IU daily
- Prevent Autism: 4000 IU while pregnant, 6,000 IU while breastfeeding study completion date Oct 2017
- Prevent Hypertension 4,000 IU
- Prevent type II Diabetes 5,000 IU
Vitamin D Clinical Trials as of Dec 2011
- "High Dose" "Vitamin D" 63 trials
- pharmacological AND "vitamin d" 821 trials
- pharmacological AND "vitamin d" Interventional Studies 753 trials
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Some new vitamin D intervention Clinical Trials as of Nov 2011
- Is 2,000 IU cost-effective to prevent childhood colds and asthma in the winter?
- Will 100,000 IU monthly (3,000 daily) reduce senior resident falls
159 new vitamin D US Clinical Trials for Jan-Nov 2011 - here are just the three letters of the alphabet
|
Abdominal Obesity Metabolic Syndrome 2 studies Acquired Immunodeficiency Syndrome 8 studies Acute Chest Syndrome 1 study Acute Coronary Syndrome 1 study Acute Lung Injury 1 study Acute Lymphoblastic Leukemia 1 study Acute Respiratory Distress Syndrome 1 study Adenocarcinoma 1 study Adenocarcinoma of the Appendix 1 study Adenocarcinoma, Mucinous 1 study Albuminuria 1 study Alopecia 1 study Alopecia Areata 1 study Alzheimer Disease 3 studies Anemia 5 studies Anemia, Hemolytic 4 studies Anemia, Hemolytic, Congenital 4 studies Anemia, Iron-Deficiency 1 study Anemia, Sickle Cell 3 studies Angina Pectoris 1 study Angina, Unstable 1 study Angioedema 1 study Anorexia 1 study Anorexia Nervosa 1 study Aortic Valve Stenosis 1 study Apnea 2 studies Apraxias 1 study |
Arterial Occlusive Diseases 3 studies Arteriosclerosis 3 studies Arteriovenous Fistula 1 study Arteriovenous Malformations 1 study Arthritis 4 studies Arthritis, Rheumatoid 3 studies Asthma 7 studies Autistic Disorder 1 study Autoimmune Diseases 12 studies Autoimmune Diseases of the Nervous System 5 studies Avitaminosis 45 studies Bacterial Infections 3 studies Barrett Esophagus 1 study Behavioral Symptoms 1 study Beta-Thalassemia 1 study Birth Weight 1 study Body Weight 13 studies Bone Diseases 13 studies Bone Diseases, Endocrine 1 study Bone Diseases, Metabolic 13 studies Brain Diseases 4 studies Breast Diseases 1 study Breast Neoplasms 2 studies Bronchial Diseases 7 studies Bronchial Neoplasms 1 study |
Calcium Metabolism Disorders 6 studies Calculi 1 study Carbamoyl-Phosphate Synthase I Deficiency Disease 45 studies Carcinoma 3 studies Carcinoma, Basal Cell 1 study Carcinoma, Bronchogenic 1 study Carcinoma, Non-Small-Cell Lung 1 study Cardiomegaly 4 studies Cardiovascular Abnormalities 1 study Carpal Tunnel Syndrome 1 study Central Nervous System Diseases 4 studies Cerebral Infarction 1 study Cerebrovascular Disorders 1 study Charcot-Marie-Tooth Disease 1 study Chest Pain 1 study Child Development Disorders, Pervasive 1 study Cognition Disorders 3 studies Colonic Diseases 1 study Colonic Neoplasms 1 study Colorectal Neoplasms 1 study Congenital Abnormalities 3 studies Connective Tissue Diseases 5 studies Constriction, Pathologic 1 study Coronary Artery Disease 3 studies Coronary Disease 3 studies Critical Illness 1 study Crohn Disease 1 study Cumulative Trauma Disorders 1 study Cystadenocarcinoma 1 study Cystic Fibrosis 2 studies etc. |
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
International Clinical Trials by WHO
March 2011 : International Clinical Trials (including US)
- 1316 with vitamin D anywhere
- 596 with Vitamin D in title
- 653 Vitamin D intervention
Updated every Tuesday
- Australian New Zealand Clinical Trials Registry
- ClinicalTrials.gov = US
- ISRCTN'
Updated every 4th Tuesday
- Chinese Clinical Trial Register
- Clinical Trials Registry - India
- German Clinical Trials Register
- Iranian Registry of Clinical Trials
- Japan Primary Registries Network
- Sri Lanka Clinical Trials Registry
- The Netherlands National Trial Register
Update: WHO Clinical Trials with Vitamin D intervention – July 2011
- - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Jan 2011
712 Vitamin D US Clinical Trials updated since Jan 2010
391 INTERVENTION trials updated since Jan 2010
Trials now go beyond just noticing deficiency, they are now adding vitamin D and seeing the results = INTERVENTION
Vitamin D INTERVENTION trials in the following disease categories
Bacterial and Fungal Diseases
Behaviors and Mental Disorders
Blood and Lymph Conditions
Cancers and Other Neoplasms
Digestive System Diseases
Diseases and Abnormalities at or before Birth
Ear, Nose, and Throat Diseases
Gland and Hormone Related Diseases
Heart and Blood Diseases
Immune System Diseases
Injuries, Poisonings, and Occupational Conditions
Mouth and Tooth Diseases
Muscle, Bone, and Cartilage Diseases
Nervous System Diseases
Nutritional and Metabolic Diseases
Parasitic Diseases
Respiratory Tract (Lung and Bronchial) Diseases
Skin and Connective Tissue Diseases
Symptoms and General Pathology
Urinary Tract, Sexual Organs, and Pregnancy Conditions
Viral Diseases
10 studies Vitamin D meal
Examples
1 Completed Vitamin D Status After Single Oral Dose of Cholecalciferol in Low Fat Meal Compared to High-fat Meal
2 Recruiting The Effect of a Meal on Vitamin D Absorption
71 Intervention trials updated between Jan 1, 2011 and Jan 20, 2011
Examples
1 Recruiting Vitamin D and Osteoporosis Prevention in Elderly African American Women
2 Active, not recruiting Prevention of Vitamin D Deficiency
3 Not yet recruiting The Effect of Supplementation With Two Different Doses of Vitamin D on Bone Mineral Density, Vitamin D Levels and Hand Grip Strength in Children With Diabetes Mellitus Type 1
6 Active, not recruiting Effects of Vitamin D Replacement in Patients With Primary Hyperparathyroidism (PHPT)
9 Recruiting Vitamin D Intervention in Infants - Pilot
11 Recruiting Vitamin D in Postmenopausal Women at High Risk for Breast Cancer
12 Recruiting A Pilot Study on the Effect of Vitamin D Treatment in Patients With Statin-Associated Myalgia
13 Recruiting Clinical Effects of Vitamin D Repletion in Patients With Parkinson's Disease
14 Recruiting Impact of Vitamin D Supplementation on Lactation Associated Bone Loss
17 Recruiting Vitamin D and Coronary Calcification Study
20 Recruiting Calcium + Vitamin D Supplementation for Low Bone Mass in Adolescent Idiopathic Scoliosis (AIS)
50 Recruiting A Study of Pre-Operative Treatment of Newly-Diagnosed, Surgically-Resectable Osteosarcoma With Doxorubicin, Ifosfamide, Etoposide, and Cisplatin With Early Metabolic Assessment of Response
Map of the vitamin D clinical trials around the world - updated since Jan 2010
See also at VitaminDWiki
- Vitamin D trials, studies, and meta-analysis - Dec 2010
- Clinical Trials Vitamin D - Feb 2010 - full list of names - which can be searched
- Clinical Trials update Sept 2010 includes grouping by some major diseases
- Intervention - add vitamin D and see what happens
- includes Ultraviolet and world wide clinical trials
- 622 vitamin D Clinical Trials - June 2010
See also on web
- Patients Like Me
You can signup to indicate the type of trial you want to participate in. They will inform you when there is one in your area - WikiPedia on Clinical Trials