Serum levels of various vitamins in periodontal health and disease- a cross sectional study
J Oral Biol Craniofac Res . 2023 Jul-Aug;13(4):471-475. doi: 10.1016/j.jobcr.2023.05.009
Mayank Hans 1, Praveen Kumar Malik 2, Veenu Madaan Hans 1, Ashi Chug 3, Mayank Kumar 3
Objectives: Vitamins are micronutrients that are required in small or trace amounts. They play an essential role in the metabolism and maintenance of tissue function. This investigation aimed to assess if a deficiency of certain essential vitamins is a risk factor for developing periodontitis.
Methods: The subject population consisted of 100 subjects, 50 with generalized chronic periodontitis and 50 periodontally healthy volunteers. The following clinical parameters were measured: Gingival Index, pocket depth (mm); Clinical Attachment Loss (mm). Serum samples were collected and analyzed for levels of cis-߭carotene, ߭cryptoxanthin, vitamin B 12, folate, vitamin D, and vitamin E. Individual data collected was summarized and analyzed using statistical software.
Results: All the clinical parameters for periodontal status in the periodontitis group compared to healthy volunteers were highly significant (p < 0.0001). The mean levels of all the micronutrients, vitamin A precursors cis-߭carotene and ߭cryptoxanthin, folate, vitamin B 12, D & E were lower in the periodontitis group than the healthy volunteers, although the difference was statistically significant only in case of ߭cryptoxanthin, Vitamin B12 and Vitamin D (p < 0.05).
Conclusions: The findings of our study suggest that serum micronutrient levels especially Vitamin A, Vitamin B 12, and Vitamin D may be modifiable risk factors for periodontal disease. Providing an optimized combination of various vitamins in each meal in combination with sufficient measures of standard oral hygiene care may provide an important role in the prevention of periodontitis.
Download the PDF from VitaminDWiki
VitaminDWiki – Dental category contains
Some Dental studies
- Vitamin D cut dental caries in half 80 years ago – meta-analysis 2013 80 years ago
- Caries (tooth decay) and Vitamin D - 23+ studies
- Periodontitis reduced by Vitamin D - many studies
- Risk of Oral Surgery reduced by Vitamin D – scoping review Nov 2021
- Some Dental Malocclusions 5X more likely if low vitamin D – June 2021
- Grinding teeth while sleeping (sleep bruxism) 6 X more likely if low vitamin D – Jan 2021
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
7 Intervention AND Dental studies 19 items listed in BOTH Dental and Infant or Child 7 listed in BOTH Dental and Vitamin D Receptor
23+ VitaminDWiki pages contain PERIODONTITIS in title
VitaminDWiki pages containing PERIODONTITIS in title
VitaminDWiki – Vitamin B12 contains
Vitamin B12 is not a cofactor of Vitamin D, but it is often needed with Vitamin D
Surfing the web finds- B12 deficiency increases with age
- B12 appears to have no toxic upper limit
- Some people get frequent B12 injections or I.V, to restore levels
- Injection may not be needed
- Only a small portion of B12 taken orally gets into the bloodstream
- Sublingual B12 may not have that problem
- B12 is stored in the liver – half-life of > 2 years - But. Dr. Greger says to take it weekly or daily
- B12 deficiency symptoms include poor gut - which can reduce uptake of Vitamin D
- unless use gut-friendly forms of Vitamin D, including topical
- B12 can be supplemented via pills, sublingual, transdermal patch, injection, emulsion, and spray
- As with Vitamin D, a massive (loading) dose can restore levels quickly
- Nano forms of B12 are more bio-available - as with many other supplements
57 items in Vitamin B12 category on VitaminDWiki Chronic periodontitis associated with low vitamin D and low vitamin B12 – May 2023Printer Friendly Follow this page for updates698 visitors, last modified 02 Jun, 2023, This page is in the following categories (# of items in each category)