Loading...
 
Toggle Health Problems and D

COVID in hospital fought by Vitamin D (25,000 IU daily for 4 days, then 25K weekly) - RCT – July 2022


Positive Effects of Vitamin D Supplementation in Patients Hospitalized for COVID-19: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients 2022, 14(15), 3048; https://doi.org/10.3390/nu14153048
Sophie De Niet et.all

Image

Image
Retrospective studies showed a relationship between vitamin D status and COVID-19 severity and mortality, with an inverse relation between SARS-CoV-2 positivity and circulating calcifediol levels. The objective of this pilot study was to investigate the effect of vitamin D supplementation on the length of hospital stay and clinical improvement in patients with vitamin D deficiency hospitalized with COVID-19. The study was randomized, double blind and placebo controlled. A total of 50 subjects were enrolled and received, in addition to the best available COVID therapy, either vitamin D (25,000 IU per day over 4 consecutive days, followed by 25,000 IU per week up to 6 weeks) or placebo.
The length of hospital stay decreased significantly in the vitamin D group compared to the placebo group (

  • 4 days vs. 8 days; p = 0.003).

At Day 7, a significantly lower percentage of patients were

  • still hospitalized in the vitamin D group compared to the placebo group (19% vs. 54%; p = 0.0161),

and none of the patients treated with vitamin D were hospitalized after 21 days compared to 14% of the patients treated with placebo.
Vitamin D significantly reduced the duration of supplemental oxygen among the patients who needed it (4 days vs. 7 days in the placebo group; p = 0.012) and significantly improved the clinical recovery of the patients, as assessed by the WHO scale (p = 0.0048). In conclusion, this study demonstrated that the clinical outcome of COVID-19 patients requiring hospitalization was improved by administration of vitamin D.
 Download the PDF from VitaminDWiki

Note: All participants initially had <20 ng of vitamin D


VitaminDWiki - 43 studies in both categories Virus and Intervention

This list is automatically updated


VitaminDWiki – COVID-19 treated by Vitamin D - studies, reports, videos

As of Jan 31, 2024, the VitaminDWiki COVID page had:  19+ trial results,   37+ meta-analyses and reviews,   Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   All 26 COVID risk factors are associated with low Vit D,   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   166 COVID Clinical Trials using Vitamin D (Aug 2023)   Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries


Created by admin. Last Modification: Sunday October 2, 2022 01:07:28 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
18533 COVID 25K table.jpg admin 02 Oct, 2022 146.61 Kb 193
18532 COVID 25,000.jpg admin 02 Oct, 2022 38.41 Kb 244
18531 COVID 25K_CompressPdf.pdf admin 02 Oct, 2022 217.33 Kb 158