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A paltry 400 IU Vitamin D recommended during pregnancy - NICE UK Dec 2018

NICE (National Institute of Health Care Excellence) Summary

NICE 2018 previous guidelines = 2008

Just 400 IU of daily Vitamin D reduced miscarriage (recurrent) by 3.5 times – RCT July 2016
- 400 IU is thus proven to provide some benefit
UK proposes that 10 ng level and 400 IU is enough Vitamin D for everybody (no and no)- July 2015
Vitamin D pill meets new UK guidelines (400 IU) - Dec 2016
Intervention - Vitamin D Of the 330 trials, only 4 found success with 400 IU vitamin D (Dec 2016)
- Note: Only Korea recommends a smaller dose size = 200 IU
4,000 IU of Vitamin D is OK - 19 organizations agree - 2018

Benefits of >4,000 IU during pregnancy

Healthy pregnancies need lots of vitamin D has the following summary

Problem	Vit. D Reduces	Evidence
0. Chance of not conceiving	3.4 times	Observe
1. Miscarriage	2.5 times	Observe
2. Pre-eclampsia	3.6 times	RCT
3. Gestational Diabetes	3 times	RCT
4. Good 2nd trimester sleep quality	3.5 times	Observe
5. Premature birth	2 times	RCT
6. C-section - unplanned	1.6 times	Observe
Stillbirth - OMEGA-3	4 times	RCT - Omega-3
7. Depression AFTER pregnancy	1.4 times	RCT
8. Small for Gestational Age	1.6 times	meta-analysis
9. Infant height, weight, head size within normal limits		RCT
10. Childhood Wheezing	1.3 times	RCT
11. Additional child is Autistic	4 times	Intervention
12.Young adult Multiple Sclerosis	1.9 times	Observe
13. Preeclampsia in young adult	3.5 times	RCT
14. Good motor skills @ age 3	1.4 times	Observe
15. Childhood Mite allergy	5 times	RCT
16. Childhood Respiratory Tract visits	2.5 times	RCT

RCT = Randomized Controlled Trial

Pregnancy category starts with

886 items in Pregnancy category

- see also

Overview Pregnancy and vitamin D
Number of articles in both categories of Pregnancy and:Dark Skin 28; Depression 21; Diabetes 44; Obesity 15; Hypertension 44; Breathing 35; Omega-3 40; Vitamin D Receptor 24 Click here for details
All items in category Infant/Child 823 items
Pregnancy needs at least 40 ng of vitamin D, achieved by at least 4,000 IU – Hollis Aug 2017
38+ papers with Breastfed etc, in the title
Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019
53+ preeclampsia studies
94+ studies with PRETERM in the title
Fertility problem (PCOS) reduced by vitamin D: many studies 15+
94+ Gestational Diabetes
Caesarean birth much more likely if low Vitamin D - many studies 15+ studies
Post-partum depression and low Vitamin D - many studies 15+ studies
Stillbirth reduced by Vitamin D, Zinc, Omega-3 - several studies 5+ studies
Search VitaminDWiki for "Assisted reproduction" 33 items as of Aug 2022
Fertility and Sperm category listing has 134 items along with related searches
(Stunting OR “low birth weight” OR LBW) 1180 items as of June 2020
Less labor pain if higher level of vitamin D – August 2021
Healthy pregnancies need lots of vitamin D
Ensure a healthy pregnancy and baby - take Vitamin D before conception

A paltry 400 IU Vitamin D recommended during pregnancy - NICE UK Dec 2018

3747 visitors, last modified 17 Dec, 2018,

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- WHO recommends zero vitamin D during pregnancy, rest of the world disagrees – 2018, 2020

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