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8 ways that Cancer might be prevented by Vitamin D - June 2019

Potential Molecular Mechanisms of the Anti-cancer Activity of Vitamin D

Anticancer Research 39: 3353-3363 (2019). doi: 10.21873/anticanres. 13478
DOROTA SKRAJNOWSKA and BARBARA BOBROWSKA-KORCZAK
Department of Bromatology, Medical University of Warsaw, Warsaw, Poland

VitaminDWiki

Cancer category starts with the following

Cancers get less Vitamin D when there is a poor Vitamin D Receptor


Vitamin D Receptor and Cancers

Items in both categories Vitamin D Receptor and Cancer - Breast:

Items in both categories Vitamin D Receptor and Cancer - Colon:

Items in both categories Vitamin D Receptor and Cancer

Items in both categories Vitamin D Receptor and Cancer - other:

Items in both categories Vitamin D Receptor and Cancer - Skin:

Items in both categories Vitamin D Receptor and Cancer - Prostate:

Items in both categories Vitamin D Receptor and Cancer - Ovarian:

 Download the PDF from Sci-Hub via VitaminDWiki

Vitamin D, or more precisely its active metabolite calcitriol (1,25-(OH)2D3), plays a fundamental role in bone metabolism and differentiation as well as in intestinal absorption of calcium and regulation of calcium-phosphate metabolism. Recent decades have brought about the discovery of the role of calcitriol in processes regulating cell differentiation, proliferation, angiogenesis and apoptosis. This creates the potential for numerous therapeutic applications of vitamin D in diseases associated with autoaggressive immune responses or in cancer. This study presents selected issues regarding current knowledge of the anti-cancer mechanisms of vitamin D.
Sections = ways
Vitamin D - Cell Cycle Regulation
Nuclear Vitamin D Receptor (nVDR)
Vitamin D - Apoptosis Induction
Vitamin D - Inhibition of Invasiveness and Metastasis of Tumours
Vitamin D - Angiogenesis Inhibition
Inhibition of Hedgehog (Hh) Signaling by Vitamin D
Interaction of p53 and VDR Signaling
Vitamin D - Interaction of Photocarcinogenesis
Conclusion
On the basis of current data, it cannot be stated conclusively whether intake of vitamin D may offer protection against cancer. The presence of the VDR throughout the body and the effect of vitamin D on the cell cycle, apoptosis, angiogenesis, Hh signaling, interaction of p53 and photocarcinogenesis unquestionably suggest such a potential. However, further research is required, first to fully elucidate the mechanisms of action of this vitamin, and secondly to determine a specific dose and time of intake necessary to achieve an anticancer effect.

Created by admin. Last Modification: Monday December 30, 2019 12:45:49 GMT-0000 by admin. (Version 3)

Attached files

ID Name Comment Uploaded Size Downloads
13235 Cancer Sci-Hub.pdf PDF 2019 admin 26 Dec, 2019 21:49 208.24 Kb 45
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