Loading...

Toggle Health Problems and D

50,000 IU monthly safe to take without any vitamin D testing – RCT Dec 2013

A Double-Blind, Placebo Controlled, Randomized Trial to Assess the Impact of a Monthly Administration of 50,000 IU of Vitamin D3 for 6 Months on Serum Levels of 25-Hydroxyvitamin D in Healthy Young Adults.

Int J Endocrinol. 2013;2013:652648. Epub 2013 Nov 13.
Brunel E, Schnitzler M, Foidart-Dessalle M, Souberbielle JC, Cavalier E.
Departments of General Medicine, University of Liege and Liege University Hospital, 4000 Liège, Belgium.

In this double blind, unicentre, randomized, placebo controlled study, we evaluated the changes in 25-hydroxyvitamin D (25(OH)D) serum levels in 150 young Belgian adults (18-30 years), monthly supplemented with 50,000 IU of vitamin D (VTD) or placebo for 6 months, from November 2010 to May 2011.
At T0, 30% of the population presented 25(OH)D serum levels below 20 ng/mL. In the VTD-treated group, mean serum levels increased from 21.2 ± 8.2 to 30.6 ± 8.8 ng/mL (P < 0.001) at T3mo and to 36.0 ± 9.2 ng/mL (P < 0.001) at T6mo.
Despite documented VTD intake, no changes in serum levels were, however, observed in 10% of the treated group.

(Comment by VitaminDWiki – note that this study was during the winter and that the placebo group dropped by 11 ng)

In the placebo group, mean 25(OH)D serum levels decreased from 22.8 ± 8.5 to 14.0 ± 6.9 ng/mL at T3mo (P < 0.001) but returned to values not significantly different from those observed at T0 (23.5 ± 8.6 ng/mL) at T6mo. No difference between serum calcium levels was observed between the groups throughout the study. In conclusion, monthly supplementation with 50,000 UI of VTD in winter can warrant serum 25(OH)D levels above 20 ng/mL in 96.2% of those healthy young adults without inducing unacceptably high 25(OH)D concentration. This supplementation is safe and may be proposed without 25(OH)D testing.

PMID: 24324493

See also VitaminDWiki

see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=2475

50,000 IU monthly safe to take without any vitamin D testing – RCT Dec 2013

6276 visitors, last modified 22 Dec, 2014,

(Cached) Printer Friendly Follow this page for updates

Links to this page
- Low-cost Vitamin D testers (two yes-no tests for 11 dollars) - 2024 Low cost vitamin D Blood Tests Vitamin D Status estimation of elderly by questionnaire – Oct 2017 France restricts Vitamin D testing to 4 health problems, paper proposes 5 more – Nov 2016 Vitamin D test costs reimbursed in Japan – Aug 2016 France restricts payments for Vitamin D tests – Dec 2015 How should Vitamin D be tested – a changing landscape – June 2016 Shape Magazine recommends a max of 1,000 IU of vitamin D (wrong) - Dec 2014 No vitamin D test needed before supplementing (typically) – April 2014 20 cent vitamin D pill similar to 2 hours sunbathing at 60 degree latitude – RCT Aug 2013

This page is in the following categories (# of items in each category)

Tests for Vitamin D 149

Edit

“One pill every two weeks fights diabetes, cancers, heart failure, and 21 other diseases.”

Click for details

Health Problems and D

15,500+ pages in VitaminDWiki
Topic (# in topic)

Acne (20+ studies)

Attention Deficit Hyperactivity Disorder/ADHD (49+)

Alcohol (29+)

Allergy (120+) Overview

Amyotrophic Lateral Sclerosis/ALS (30+)

Alzheimer's (81+) Overview

Ankylosing Spondylitis (20+)

Antibiotics/Probiotics (92+) Overview

Asthma (145+) Overview

Atopic Dermatitis Overview (18+)

Autism (157+) Overview

Vit. D Receptor (14+)

Transgender (19+)

Autoimmune (199+)

Systemic Sclerosis (10+)

Back Pain (43+)

Lumbar Degeneration (14+)

Bipolar Disorder (16+)

Bone - Health (311+)

BMD, Bone loss (55+)

Breathing (450+)

Hay Fever (20+)

Pneumonia (50+)

Respiratory (82+)

Burns/Wounds (30+)

Cancer (292+) Overview

After diagnosis (113+)

Bladder (28+)

Bone (8+)

Breast (256+) Overview

Child (16+)

Colon (144+) Overview

Endometrial (5+)

Gastric (9+)

Leukemia (19+)

Liver (17+)

Lung (55+) Overview

Lymphoma (26+)

Mg and Cancer (13+)

Melanoma (43+)

Multiple Myeloma (10+)

Metastatic (17+)

Other (66+)

Ovarian (26+)

Palliative Care (10+)

Pancreatic (57+)

Prostate (103+) Overview

Skin (121+) Overview

Survive (37+)

Thyroid (7+)

{DIV}

Cardiovascular (526+) Overview

Atherosclerosis (56+)

Atrial Fibrillation (20+)

Heart Failure (47+)

HRV (10+)

Omega-3 (38+)

Statins (80+)

Carpal Tunnel Syndrome (12+)

Cerebral Palsy (6+)

Cholesterol (52+) Overview

Chronic Fatigue (7) Overview

Cognitive (389+) Overview

Anesthesia ==> Cog

Brain (103+)

Delirium (9+)

Dementia (50+)

Mental Illness (300+)

Mental Stress (10+)

Colds/flu Overview

Concussions (25+)

Chronic obstructive pulmonary disease/COPD (17+)

COVID-19 (1300+)

Cystic Fibrosis (51+)

Dental (116+)

Fluoridation (16)

Depression (267+)

Anxiety ( 11+)

Omega-3 (29)

SAD (9)

Diabetes (548+) Overview

Hemodialysis (41+)

Magnesium (27+)

Meta-analyses (39+)

Metabolic Syndrome + Mg

Neuropathy (15+)

Prediabetes (30+)

Red Meat (4+)

Retinopathy (8+)

Type 1 Diabetes (46+)

Vitamin D Receptor (23+)

Zinc (5+)

Diseases general (93+)

Ear (17+)

Otitis Media (10+)

Endometriosis (8+)

Falls/Fractures (258+) Overview

Fatigue, Chronic Overview

Fertility/Sperm (141+)

Erectile Dysfunction (12+)

In Vitro Fert. (18+)

Testosterone (14+)

Fibromyalgia Overview

Fractures Overview

Ankle (16+)

Bone & Stress Fractures

Bone Mineral Density (28+)

Children (16+)

Hip Fractures (68+)

Vertigo (22+)

Genetics (343+)

CYP24A1 (31+)

CYP24R1 (25+)

CYP27B1 (62+)

Epigenetics (18+)

Telomere (12+)

Vit D Binding (177+)

Vit D Receptor (517+)

Cancer in VDR (79+)

Gestational Diabetes (34+)

Gout (13+)

Gut (206+) Overview

Bariatric (15+)

Celiac (7+)

Clostridium difficile (9+)

Crohn's (38+)

IBD (28+)

IBS (18+)

Ulcerative Colitis (12+)

Hair (20+)

Alopecia Areata (8+)

Health - general (109+)

Human Immunodeficiency Virus/HIV (45+) Overview

Hives (10+)

Hypertension (166+) Overview

Pregnancy (41+)

Hyperparathyroid Overview

Immunity (273+)

Inflammation (173+)

CRP (19+)

Infection (141+)

Influenza Overview

Kidney (228+) Overview

Chronic Kidney (63+)

Dialysis (39+)

Kidney Stones (29+) Overview

Leprosy (16+)

Liver (102+) Overview

Hepatitis-B (12+)

Hepatitis-C (13+)

NAFLD (27+)

Lyme Disease (9+)

Lupus (77+)

Mental Illness (20+)

Mental Stress (5+)

Metabolic Syndrome (105+) Overview

Mortality (296+)

Multiple Sclerosis (412+) Overview

Genetics and Receptor (32+)

Virus (16+)

Muscle (113+)

Handgrip (12+)

Sarcopenia (30+)

Muscular Dystrophy (9+)

Myopia (17+)

Obesity (441+)Overview

Child & Youth (60+)

Vitamin D Receptor (16+)

Virus and Obesity (25+)

Weight Loss (31+)

Osteoarthritis (60+) Overview

Knee (26+)

Osteoporosis (218+) Overview

BMD (26+)

Pain - chronic (165+) Overview

Magnesium (13+)

Pancreatitis (20+)

Parkinson's (117+) Overview

Pneumonia (22+)

Pollution (31+)

Pregnancy (918+) Overview

Breastfed (38+)

Caesarean (15+)

Depression (21+)

Dark Skin (30+)

Gestational Diabetes (41+)

In Vitro Fert. (18+)

Iodine (21+)

Low Birth Weight (23+)

Magnesium (30+)

Miscarriage (31+)

Multiple Sclerosis (13+)

Omega-3 before and during (49+)

PCOS (15+)

Preeclampsia (55+)

Preterm (125+)

Preterm - Omega-3 (13+)

Stillbirth (8+)

Prostate - BPH (16+)

Psoriasis (72+)

Respiratory Tract Infection/RTI (8+)

Restless Legs Syndrome (15+)

Rheumatoid Arthritis (117+) Overview

Juvenile RA (9+)

Rickets (127+) Overview

Sarcopenia (28+)

Schizophrenia Overview

Sepsis (201+)

Sickle Cell (20+) Overview

Skin (120+) Overview

Aging

Atopic Dermatitis(27+)

Hives

Vitiligo (8+)

Sleep (101+)

Sleep Apnea(12+)

Smoking (83+)

Spinal Cord (20+)

Spinal Surgery (13+)

Statins (40+)

Stroke (131+) Overview

Cognitive Impairment (15+)

Depression (9+)

Ischemic (21+)

Thyroid/Parath. (82+) Overview

PTH (34+)

Trauma/Surgery (347+)

Bariatric surgery (12+)

Bone surgery (23+)

ICU & Loading Dose (69+)

Need Vit D (69+)

Ortho. & Hip (69+)

Sepsis (41+)

Transplant (31+)

Traumatic Brain Injury (24+)

Tuberculosis (124+) Overview

Urinary Tract Infection (15+)

Virus (1391+)

All studies

Bird Flu

Cardiovascular (19+)

Cancers after VAX (17+)

Child - years after VAX (11+)

Cognitive (10+)

Dengue (27+)

Epstein-Barr Virus (20+)

Excess Deaths (23+)

Hepatitis (29+)

Herpes or Shingles (13+)

Ivermectin (35+)

Long-COVID (72+)

Magnesium (60+)

Masks (11+)

Meta-analyses (40+)

Omega-3 (14+)

Pfizer (20+)

RSV (12+)

Ultraviolet light (16+)

Vaccination (198+)

Vitamin D (650+)

Vitamin D Receptor (31+)

Vitamin K

Zinc (32+)

Vision (110+)

Cataracts (12+)

Dry Eye (15+)

Glaucoma (8+)

Macular Degeneration (14+)

Myopia (20+)

People and Low Vitamin D

Infant/Child (850+)

Allergy (36+)

Cancer (13+)

Cerebral Palsy (15+)

Down Syndrome (5+)

Fracture, low energy (10+)

Growing Pains (10+)

Pneumonia (25+)

Preemie (25+)

Puberty early if low D (9+)

Respiratory (21+)

RSV (25+)

Tonsils (9+)

Vaccination (10+)

Virus (42+)

Military (27+)

Veterans (17+)

Prisoners (14+)

Seniors (431+) Overview

Aging (38+)

Essential Tremor (4+)

Frailty (20+)

Longevity (47+)

Nursing Homes (19+)

Sarcopenia (25+)

Urinary incontinence (15+)

Vertigo (22+)

Skin - Dark (460+) Overview

Pregnancies (30+)

Sports (277+) Overview

Exercise (68+)

Muscle (138+)

Traumatic Brain Inj. (24+)

Women (196+) Overview

Endometriosis (25+)

Incontinence (16+)

Menopause (17+)

PCOS

Premenstrual Syndrome (20+)

Uterine Fibroid (13+)

Yeast Infection

Youth (173+)

Early Puberty (15+)

Locations

World (14+)

Aust NZ (68+)

Africa (28+)

Europe (233+)

India (65+)

Iceland (40+)

Middle East (152+)

Orient (76+)

Russia (12+)

Scotland (20+)

Far from Equator (124+)

Click here to search the site
A list includes 282+ pages having many studies
# of studies as of Oct 20, 2024