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4,000 IU of vitamin D for 1 month does not help (muscles in this case) – RCT Jan 2020

Supplemental Vit D3 Does Not Affect Musculoskeletal or Psychomotor Performance in College Aged Males

Int J Vitam Nutr Res. , 1-6 2020 Jan 23. DOI: 10.1024/0300-9831/a000631
David Bellar 1, Kellie Murphy 2, Greggory R Davis 3, Lawrence W Judge 4

The experiment examined the effects 4 weeks of vitamin D (Vit D) supplementation versus placebo on musculoskeletal and psychomotor performance. Thirty-two college age males (Age: 22 ± 4 y, Height: 177.7 ± 8.3 cm, Weight: 81.5 ± 14.6 kg, BF%: 19.6 ± 7.9, Vit D: 20.0 ± 7.2 ng/ml). Participants were assigned to group (Vit D vs placebo) and remained blind throughout the study. The treatments were 4000 IU of Vit D3 or placebo (dextrose) administered daily for 4 weeks. The participants underwent baseline testing for isometric strength, explosive ability and psychomotor performance, which was repeated at week 2 and week 4. Isometric tests consisted of an Isometric Mid Thigh Pull on a Force Plate (IMTP) and an upper body isometric test (UBIST) using a load cell. Peak force during a countermovement jump (CMJ) was also determined via force plate. A psychomotor vigilance test (PVT) was used to measure sustained reaction time. Analysis of the UBIST data did not reveal a significant group × time interaction (p = 0.14; Vit D pre: 553.7 ± 168.3 N, post: 585.5 ± 150.2 N; Placebo pre: 677.7 ± 182.3 N, post: 649.8 ± 236.9 N). For IMTP no significant group × time interaction (p = 0.83; Vit D pre: 2596.4 ± 342.3 N, post: 2606.9 ± 378.3 N; Placebo pre: 2684.0 ± 432.9 N, post: 2762.6 ± 440.4 N) was found. CMJ analysis did not reveal interaction effects for group × time (p = 0.21; Vit D pre: 4429.7 ± 1619.0 N, post: 4938.5 ± 2374.8 N; Placebo pre: 5537.3 ± 3027.0 N, post: 6266.9 ± 4577.3 N). For PVT (mean reaction time) there was no significant interaction effects for group × time (p = 0.35; Vit D pre: 0.304 ± 0.041 sec, post: 0.301 ± 0.053 sec; Placebo pre: 0.295 ± 0.044 sec, post: 0.284 ± 0.029 sec). In conclusion, four weeks of Vit D supplementation was not effective in increasing musculoskeletal or psychomotor performance.