Loading...
 
Toggle Health Problems and D

COVID-19 test positive 4.5 X more likely if had low vitamin D test within 4 years – Jan 6, 2021

Increased risk for COVID-19 in patients with vitamin D deficiency

Nutrition Volume 84, April 2021. https://doi.org/10.1016/j.nut.2020.111106
JosephKatzD.M.D.aSijiaYueM.Sc.bWeiXuePh.D.b
Image

VitaminDWiki
987,849 patients at University of Florida Hospital
32,000 tested for low vitamin D sometime since Oct 2015
887 Tested positive for COVID-19 in 2020
87 both tested positive and had low Vitamin D

Note: Probably only a small fraction of those with low vitamin D actually were tested
  Medicare, for example, will pay for only a single vitamin D test in a lifetime

Note: Some of the tests will have been done in the Spring, Summer, Fall
   and the person could test OK during that season, but not in the winter

Note: Testing low probably was <20 ng/ml.
   COVID-19 appears to be only fought by Vitamin D when > 30 or 40 ng


Virus meta-analyses

COVID-19 treated by Vitamin D - studies, reports, videos

As of Jan 31, 2024, the VitaminDWiki COVID page had:  19+ trial results,   37+ meta-analyses and reviews,   Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   All 26 COVID risk factors are associated with low Vit D,   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   166 COVID Clinical Trials using Vitamin D (Aug 2023)   Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries

 Download the PDF from VitaminDWiki

Objective
The 2019 coronavirus disease (COVID-19) pandemic has disproportionally affected a variety of patients with underlying risk factors such as respiratory and cardiovascular diseases, diabetes, obesity, and black race. Vitamin D deficiency, which can result in a compromised immune response, has been also linked to increased risk and increased morbidities associated with COVID-19. In the absence of large-scale longitudinal studies to determine the strength of association between vitamin deficiency and COVID-19, cross-sectional studies of large patient cohorts can be used.

Methods
We used the i2b2 patient's registry platform at the University of Florida Health Center to generate a count of patients using the international classification of diseases (ICD)-10 diagnosis codes for the period of October 1, 2015, through June 30, 2020. Logistic regression of the aggregates was used for the analysis.

Results
Patients with vitamin D deficiency were 4.6 times more likely to be positive for COVID-19 (indicated by the ICD-10 diagnostic code COVID19) than patients with no deficiency (P < 0.001). The association decreased slightly after adjusting for sex (odds ratio OR = 4.58; P < 0.001) and malabsorption (OR = 4.46; P < 0.001), respectively. The association decreased significantly but remained robust (P < 0.001) after adjusting for race (OR = 3.76; P < 0.001), periodontal disease status (OR = 3.64; P < 0.001), diabetes (OR = 3.28; P < 0.001), and obesity (OR = 2.27; P < 0.001), respectively. In addition, patients with vitamin D deficiency were 5 times more likely to be infected with COVID-19 than patients with no deficiency after adjusting for age groups (OR = 5.155; P < 0.001).

Conclusions
Vitamin D deficiency is significantly associated with increased risk for COVID-19.

Image
PD = periodontal disease
PA = periapical (dental) abscesses


Created by admin. Last Modification: Wednesday January 6, 2021 20:51:11 GMT-0000 by admin. (Version 10)

Attached files

ID Name Comment Uploaded Size Downloads
14819 Florida odds ratio.jpg admin 06 Jan, 2021 186.06 Kb 348
14818 CI all.jpg admin 06 Jan, 2021 121.19 Kb 353
14817 Increased risk for COVID-19.pdf admin 06 Jan, 2021 549.86 Kb 242