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Vitamin D should reduce hospital-acquired infections – Grant Dec 2012


Vitamin D's potential to reduce the risk of hospital-acquired infections

Dermato-Endocrinology Volume 4, 2012 - Issue 2 Dec 2021 https://doi.org/10.4161/derm.2078
Dima A. Youssef, Tamra Ranasinghe, William B. Grant. Alan N. Peiris

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Table of contents
Burden of Hospital-Acquired Infections
Antimicrobial Role of Vitamin D
Use of Vitamin D in Infectious Diseases
Bacteremias and Central Vascular Catheter-Associated Bloodstream Infections
Health Care-Associated Pneumonia and Hospital-Acquired Pneumonia
Clostridium difficile Infections
Catheter-Associated Urinary Tract Infections
Surgical Site Infections
Infections due to Virulent Organisms, such as MRSA
Appropriate Dose of Vitamin D

Clipped from PDF
"To note that most recently, Cannell announced that it has become possible to prescribe vitamin D3, as 50,000 IU once weekly, and it can also be prescribed as once every 2 weeks.118"

Health care–associated and hospital-acquired infections are two entities associated with increased morbidity and mortality. They are highly costly and constitute a great burden to the health care system. Vitamin D deficiency (< 20 ng/ml) is prevalent and may be a key contributor to both acute and chronic ill health. Vitamin D deficiency is associated with decreased innate immunity and increased risk for infections. Vitamin D can positively influence a wide variety of microbial infections.

Herein we discuss hospital-acquired infections, such as pneumonia, bacteremias, urinary tract and surgical site infections, and the potential role vitamin D may play in ameliorating them. We also discuss how vitamin D might positively influence these infections and help contain health care costs. Pending further studies, we think it is prudent to check vitamin D status at hospital admission and to take immediate steps to address existing insufficient 25-hydroxyvitamin D levels.
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