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Vitamin D levels at Mayo Clinic increased over a decade – June 2018

Bone Rep. 2018 May 23;8:268-273. doi: 10.1016/j.bonr.2018.05.003. eCollection 2018 Jun.
Galior K1, Ketha H2, Grebe S1, Singh RJ1.
   This study is one of 11 others in 12 Vitamin D articles in Bone Reports Journal – 2018

 Download the PDF from VitaminDWiki

< 10 ng - decreased to 3%


25-80 ng - increased to 75%


> 80 ng - jumped to 2.5%


In early 2000's vitamin-D deficiency was shown to be prevalent in several countries including the United States (US). Studies exploring the role of vitamin-D metabolism in diverse disease pathways generated an increased demand for vitamin-D supplementation and an immense public interest in measurement of vitamin-D metabolite levels. In this report, we review the role of vitamin-D metabolism in disease processes, clinical utility of measuring vitamin-D metabolites including 25-hydroxyvitamin-D (25(OH)D), 1,25-dihydroxyvitamin-D and 24,25-dihydroxyvitamin-D and discuss vitamin-D assay methodologies including immunoassays and liquid chromatography mass spectrometry (LC-MS/MS) assays. We also provide examples of vitamin-D toxicity and insight into the trends in serum 25(OH)D levels in the US population based on 10 years of data from on serum 25(OH)D values from ~5,000,000 patients who were tested at the Mayo Medical Laboratories between February 2007-February 2017.

PMID: 29955644 PMCID: PMC6020395 DOI: 10.1016/j.bonr.2018.05.003

Created by admin. Last Modification: Thursday October 8, 2020 15:33:27 GMT-0000 by admin. (Version 13)

Attached files

ID Name Comment Uploaded Size Downloads
10059 Mayo over 80.jpg admin 30 Jun, 2018 25.09 Kb 1102
10058 Mayo 25-80.jpg admin 30 Jun, 2018 32.51 Kb 1496
10057 Mayo under 10.jpg admin 30 Jun, 2018 31.80 Kb 1133
10056 10 years at Mayo.pdf admin 30 Jun, 2018 814.50 Kb 816