- Correlative Analysis of Vitamin D and Omega-3 Fatty Acid Intake in Men on Active Surveillance for Prostate Cancer
- References
- Vitamin D and Omega-3 category starts with
- Items in both categories Prostate Cancer and Omega-3:
- Curcumin category listing has
15 items along with related searches - VitaminDWiki - Overview Prostate Cancer and Vitamin D contains:
- Vitamin D Receptor category has the following
- 55 health problems associated with poor VDR
- How to increase VDR activation
Correlative Analysis of Vitamin D and Omega-3 Fatty Acid Intake in Men on Active Surveillance for Prostate Cancer
Urology. 2021 Jun 15;S0090-4295(21)00525-2. doi: 10.1016/j.urology.2021.04.050
Rebecca A Campbell 1, Jianbo Li 2, Lindsay Malone 3, David A Levy 4Chart via Google Images
Objectves: To investigate the influence of targeted serum vitamin-D level and omega-6:3 fatty-acid ratio on prostate-specific antigen (PSA) level in men with prostate cancer managed with active surveillance by providing a nutritional intervention and vitamin supplementation.
Methods: Sixty-eight patients with biopsy-proven NCCN very-low or low-risk prostate cancer were enrolled in the prostate cancer nutrition and genetics clinic at the Cleveland Clinic from July 2013-December 2019. Patients adhered to a specific dietary regimen devoid of animal-based products and foods containing omega-6 polyunsaturated fatty acids (PUFAs). The supplement regimen consisted of: Omega-3 PUFAs 720mg (three/day); curcumin 2000 mg/day; vitamin D3 dose titrated to achieve serum level of 60 ng/ml; and vitamin B-complex 1000 mg (four times weekly). Patients underwent periodic monitoring of PSA, serum vitamin D, and PUFA levels and had frequent follow-up with the nutritionist which included a food frequency questionnaire. Interval prostate biopsy was performed as clinically indicated and/or at nine months.
Results: The mean and 95% confidence interval (CI) of PSA slope and Vitamin D serum levels slope were 0.11 (0-0.25) ng/mL/month and 4.65 (3.09-5.98) ng/mL/month, respectively. Patients with higher initial vitamin D levels were twice as likely to have a downward PSA trend (OR=2.04, 95% CI 1.04-4.01, p=0.04). Fifty-five patients underwent follow-up biopsy, all showing no progression of disease. Three patients had loose bowel movements that required omega-3 and or curcumin dose adjustments.
Conclusions: Intensive nutritional intervention with Vitamin D and Omega-3 PUFA supplementation may benefit men on active surveillance for prostate cancer and further studies are warranted.
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Vitamin D and Omega-3 category starts with
407 Omega-3 items in category Omega-3 helps with: Autism ( 7 studies), Depression ( 28 studies), Cardiovascular ( 34 studies), Cognition ( 52 studies), Pregnancy ( 44 studies), Infant ( 34 studies), Obesity ( 14 studies), Mortality ( 7 studies), Breast Cancer ( 5 studies), Smoking, Sleep, Stroke, Longevity, Trauma ( 12 studies), Inflammation ( 18 studies), Multiple Sclerosis ( 9 studies), VIRUS ( 12 studies), etc
CIlck here for details- Omega-3 should help Pancreatic Cancer in 5 ways – June 2017
- 5 supplements that flat out work (Omega-3, Vitamin D, etc.) - examine.com Oct 2017
Items in both categories Prostate Cancer and Omega-3:
- 2.5 X reduced risk of cancer in 70 year-olds by a small amount of Vitamin D, Omega-3 and exercise – RCT April 2022
- Prostate Cancer PSA reduced by 60 ng of Vitamin D, Vitamin B complex, Omega-3, Curcumin and diet – June 2021
- Men with High Omega-3 ratio 3 times less likely to have high grade prostate cancer – July 2019
- Low-Grade Prostate Cancer 70 percent less likely to progress if good level of Omega-3 – June 2018
- Prostate Cancer treatment (Vitamin D, Omega-3, Tumeric) RCT ending Dec 2018
Curcumin category listing has
15 items along with related searches - Some curcumin supplements are 100 X more bioavailable – Nov 2018
- Pancreatic cancer prevention and treatment by alternates – Vitamin D, Vitamin C, Curcumin, etc – July 2018
VitaminDWiki - Overview Prostate Cancer and Vitamin D contains:
All items in category Prostate Cancer and Vitamin D103 items Examples
- Overview Prostate Cancer and Vitamin D
- Prostate Cancer long term survival 1.7 X more likely if high level of vitamin D – Jan 2016
- High PSA readings with Prostate Cancer 4 times more likely if poor Vitamin D receptor – March 2016
- Aggressive Prostate Cancer in blacks with low vitamin D – 7X more likely if added Calcium – Jan 2017
- Probably better than 40% reduction if 40 ng of Vitamin D and minimize Calcium
- Prostate cancer in black men is 1.6 times more likely if a poor Vitamin D Receptor – Feb 2017
- Probably better than 40% reduction if 40 ng of Vitamin D and improve Receptor activation (8 ways)
- Low-Grade Prostate Cancer 70 percent less likely to progress if good level of Omega-3 – June 2018
- Might prevent Prostate Cancer with Omega-3 and Vitamin D
- Prostate Cancer PSA reduced by 60 ng of Vitamin D, Vitamin B complex, Omega-3, Curcumin and diet – June 2021
- The use of Vitamin D to prevent prostate cancer doubled in a decade – May 2019
- Prostate cancer patients in Jamaica were 5X more likely to die of PC if low vitamin D - Sept 2022
- Can take 40,000 IU of vitamin D daily before prostate cancer surgery – RCT March 2013
The Meta-analysis of Prostate Cancer
- 1.5X more likely to die of Prostate Cancer if low vitamin D when initially diagnosed – meta-analysis March 2024
- Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
- Variety of Vitamin D forms treat Prostate Cancer – RCT Review April 2019
- Prostate Cancer death 40 percent less likely if 40 ng level of vitamin D – Meta-analysis Oct 2018
- Prostate cancer risk increase with Vitamin D (other studies disagree) – meta-analysis Jan 2018
- Meta-graphs of vitamin D and Cancer – Dec 2011
- Risk of Prostate Cancer weakly associated with vitamin D - meta-analysis March 2011
- 16 percent less Prostate Cancer sometimes for each 10 ng vitamin D increase - meta-analysis Jan 2011
- Meta-analysis found vitamin D association with colon but not prostate nor breast cancer May 2010
Vitamin D prevents/treats Prostate Cancer much better when there is not excess Calcium
Prostate cancer risk increase with Vitamin D (other studies disagree) – meta-analysis Jan 2018 prevention
Prostate cancer reduced when 4000 IU vitamin D was added– Hollis RCT April 2015 treatment
7X increase in stage IV Prostate Cancer survival when vitamin D greater than 32 ng – May 2013
Never too late to have vitamin D - loading dose is great before Prostate Surgery
Vitamin D Receptor category has the following
530 studies in Vitamin D Receptor category Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
See also:
A poor VDR restricts Vitamin D from getting in the cells48 studies in the Resveratrol category It appears that 30% of the population have a poor VDR (40% of the Obese )
Health problems include: Autoimmune (
Several diseases protect themselves by deactivating the Vitamin D receptor. Example: Breast Cancer
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The Vitamin D Receptor is associated with many health problems19 studies), Breast Cancer ( 24 studies), Colon Cancer ( 13 studies), Cardiovascular ( 23 studies), Cognition ( 16 studies), Diabetes ( 24 studies), Hypertension ( 9 studies), Infant ( 22 studies), Lupus ( 6 studies), Metabolic Syndrome ( 4 studies), Mortality ( 4 studies), Multiple Sclerosis ( 14 studies), Obesity ( 17 studies), Pregnancy ( 24 studies), Rheumatoid Arthritis ( 10 studies), TB ( 8 studies), VIRUS ( 37 studies), Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation
55 health problems associated with poor VDR
A poor VDR is associated with the risk of 55 health problems click here for details
The risk of 48 diseases at least double with poor VDR as of Jan 2023 click here for details
Some health problem, such as Breast Cancer reduce the VDRVDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR
How to increase VDR activation
Compensate for poor VDR by increasing one or more:Increasing Increases 1) Vitamin D supplement Sun
Ultraviolet -BVitamin D in the blood
and thus in the cells2) Magnesium Vitamin D in the blood
AND in the cells3) Omega-3 Vitamin D in the cells 4) Resveratrol Vitamin D Receptor 5) Intense exercise Vitamin D Receptor 6) Get prescription for VDR activator
paricalcitol, maxacalcitol?Vitamin D Receptor 7) Quercetin (flavonoid) Vitamin D Receptor 8) Zinc is in the VDR Vitamin D Receptor 9) Boron Vitamin D Receptor ?,
etc10) Essential oils e.g. ginger, curcumin Vitamin D Receptor 11) Progesterone Vitamin D Receptor 12) Infrequent high concentration Vitamin D
Increases the concentration gradientVitamin D Receptor 13) Sulfroaphane and perhaps sulfur Vitamin D Receptor 14) Butyrate especially gut Vitamin D Receptor 15) Berberine Vitamin D Receptor Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above
Far healthier and stronger at age 72 due to supplements Includes 6 supplements that help the VDR
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