Diabetes (Type I, in males) became seasonal (with birth) when vitamin D supplementation was removed – Oct 2015

Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study.

J Dev Orig Health Dis. 2015 Oct 27:1-6. [Epub ahead of print]
Jacobsen R1, Moldovan M2, Vaag AA3, Hypponen E2, Heitmann BL1.
1 Research Unit for Dietary Studies, The Parker Institute, Frederiksberg Hospital, Frederiksberg, Denmark.
2 School of Population Health, University of South Australia, Adelaide, Australia.
3 Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark.

Fortification of margarine with vitamin D was mandatory in Denmark during 1961-1985. The aim of the study was to assess whether gestational and early infancy exposure to margarine fortification was associated with seasonality of birth in Danish type 1 diabetes (T1D) patients. The risks of T1D in Danes born during various exposure periods around margarine fortification termination in 1985 were analyzed.
As expected, the T1D hazards in males unexposed to margarine fortification and born in spring were higher than in males born in autumn: relevant hazard ratios (95% confidence intervals) in various exposure groups ranged from 1.74 (1.112/2.708) to 37.43 (1.804/776.558).
There were no indications of seasonality of birth in males exposed to fortification, nor in both exposed and unexposed females. The study suggests that early life exposure to low-dose vitamin D from fortified food eliminates seasonality of birth in T1D male patients. Further studies are required to investigate the identified gender differences.

PMID: 26503327

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How much vitamin D in was in the margarine?

See also VitaminDWiki

• Fortification with Vitamin D category listing has 125 items along with related searches
• ODIN: Europeans study vitamin D fortification and testing
• Type 1 diabetes starting to decrease in Finland, they started Vitamin D fortification in 2003 – July 2013
• Vitamin D home fortification- don't wait 100 years for your govt
• Diabetes category listing has 517 items along with related searches
• Overview Diabetes and vitamin D contains the following summary
• Diabetes is 5X more frequent far from the equator
• Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
• Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
• Sedentary people get less sun / Vitamin D
• Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
• Elderly get 4X less vitamin D from the same amount of sun
      Elderly also spend less time outdoors and have more clothes on
• All items in category Diabetes and Vitamin D 517 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

• Appears that >2,000 IU will Prevent
• Appears that >4,000 IU will Treat , but not cure
• Appears that Calcium and Magnesium are needed for both Prevention and Treatment
  • which are just some of the vitamin D cofactors

Number of articles in both categories of Diabetes and:
'This list is automatically updated''

• Dark Skin 24;   Intervention 55;   Meta-analysis 36;   Obesity 32;  Pregnancy 42;   T1 (child) 38;  Omega-3 11;  Vitamin D Receptor 22;  Genetics 12;  Magnesium 27    Click here to see details

Some Diabetes studies

• Glycemic control of type 2 diabetes – only Vitamin D had high quality studies – meta-analysis Sept 2022
• Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT June 2022
• Incidence of Type-2 Diabetes increased 3X in 30 years (by the way, Vitamin D helps) – July 2022
• Vitamin d treats Type II Diabetes in many ways (14 article review) - Sept 2021
• Diabetes 30 percent more likely if poor Vitamin D Receptor – meta-analysis of 47 studies – July 2021
• Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021
• Diabetes prevented by 50,000 IU vitamin D monthly (Iran) – Jan 2022
• Most Diabetics getting 40,000 IU of vitamin D weekly did not get to 30 ng (needed gut-friendly form) - RCT June 2020

50 ng of Vitamin D fights Diabetes

• Saudi study defines normal Vitamin D level to be 50 to 70 ng (diabetes, etc.) - June 2020
• Diabetes 5X less likely if more than 50 ng of Vitamin D – April 2018

T1 Diabetes

• T1 Diabetes 3X lower risk if high vitamin D (over 40 ng) – Meta-analysis Nov 2020
• Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies – Sept 2019
• Type 1 Diabetes prevention with Vitamin D and Omega-3 – Symposium April 2019

Pre-Diabetes

• Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021
• Prediabetes 1.5 X more likely to go away if take Vitamin D – meta-analysis July 2020

Diabetes, Metabolic Syndrome and Magnesium - many studies