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COVID-19 and Vitamin D – expert consensus and guidelines (Annweiler, behind paywall) – Oct 2021

Vitamin D supplementation and COVID-19: expert consensus and guidelines

Geriatr Psychol Neuropsychiatr Vieil . 2021 Oct 5. doi: 10.1684/pnv.2021.0955
Cédric Annweiler 1, Jean-Claude Souberbielle 2


After 12 months of viral circulation, the SARS-CoV-2 has infected millions of people around the world, leaving hundreds of thousands dead. Given the lack of effective therapy and vaccination against COVID-19, focusing on the immediate repurposing of existing drugs gives some hope of curbing the pandemic.

Vitamin D is a possible candidate drug which is discussed in a high number of publications.

Randomised clinical trials have shown that vitamin D supplementation significantly reduces the risk of respiratory infections.

There is also a great deal of evidence that hypovitaminosis D is an independent (and easily modifiable) risk factor for severe forms of COVID-19 and death.

Vitamin D supplementation is a simple, safe and inexpensive measure, which is effective in correcting hypovitaminosis D, present in 40-50% of the French population and in more than 80% of adults with COVID-19.

In this position paper, we propose simple regimens (adapted to the pharmaceutical forms currently available in France) for vitamin D supplementation in adults with or without COVID-19.


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