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Vitamin D (any amount) associated with one third less likely to get COVID-19 (UK Biobank) – Jan 2021

Habitual use of vitamin D supplements and risk of coronavirus disease 2019 (COVID-19) infection: a prospective study in UK Biobank

Am J Clin Nutr. 2021 Jan 29;nqaa381. doi: 10.1093/ajcn/nqaa381
Hao Ma 1, Tao Zhou 1, Yoriko Heianza 1, Lu Qi 1 2 3

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Note: Only 363 of 7934 people in UK Biobank were taking some amount of Vitamin D in 2006-2010
Biobank information is extremely out of date, and should be ignored
It is amazing that it gets past peer-review

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COVID-19 treated by Vitamin D - studies, reports, videos

As of Sept 21, 2021, the page had:  34 trials6 trial results,   23 meta-analyses and reviews,   63 observations,   35 recommendations,   55 associations,  89 speculations,  48 videos   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   26 risk factors are ALL associated with low Vit D,   Recent Virus pages   Fight COVID-19 with 50K Vit D weekly   Vaccines

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Background: Previous studies have related vitamin D supplementation to a lower risk of acute respiratory tract infection. Emerging evidence suggests that vitamin D insufficiency is related to a higher risk of coronavirus disease 2019 (COVID-19) infection.

Objectives: We aimed to investigate the prospective association between habitual use of vitamin D supplements and risk of COVID-19 infection, and assess whether such an association differed according to the different levels of circulating and genetically predicted vitamin D.

Methods: This study included 8297 adults who have records of COVID-19 test results from UK Biobank (from 16 March 2020 to 29 June 2020). The use of vitamin D supplements, circulating vitamin D levels, and main covariates were measured at baseline (2006-2010). Genetically predicted vitamin D levels were evaluated by genetic risk score.

Results: After adjustment for covariates, the habitual use of vitamin D supplements was significantly associated with a 34% lower risk of COVID-19 infection (OR, 0.66; 95% CI, 0.45-0.97; P = 0.034). Circulating vitamin D levels at baseline or genetically predicted vitamin D levels were not associated with the risk of COVID-19 infection. The association between the use of vitamin D supplements and the risk of COVID-19 infection did not vary according to the different levels of circulating or genetically predicted vitamin D (P-interactions = 0.75 and 0.74, respectively).

Conclusions: Our findings suggest that habitual use of vitamin D supplements is related to a lower risk of COVID-19 infection, although we cannot rule out the possibility that the inverse association is due to residual confounding or selection bias. Further clinical trials are needed to verify these results.


Created by admin. Last Modification: Sunday January 31, 2021 12:06:46 GMT-0000 by admin. (Version 5)

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