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Bariatric Surgery and Vitamin D - many studies

1 year after Bariatric Surgery (RYGB)
   74 lbs lost if >30 ng of Vitamin D
   48 lbs lost if <30 ng of Vitamin D
Note: Might not have needed surgery if weight loss plan + weekly 50,000 IU of Vitamin D


16+ VitaminDWiki pages have BARIATRIC in the title

This list is automatically updated


Many Bariatric Surgeries reduce absorption of vitamins and minerals - including Vitamin D

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Most people need >2,000 IU of vitamin D before and after Bariatric Surgery - meta-analysis Sept 2023

Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis
Rev Endocr Metab Disord. 2023 Sep 4. doi: 10.1007/s11154-023-09831-3
Andrea Giustina 1, Luigi di Filippo 2, Antonio Facciorusso 3, Robert A Adler 4, Neil Binkley 5, Jens Bollerslev 6, Roger Bouillon 7, Felipe F Casanueva 8, Giulia Martina Cavestro 9, Marlene Chakhtoura 10, Caterina Conte 11, Lorenzo M Donini 12, Peter R Ebeling 13, Angelo Fassio 14, Stefano Frara 2, Claudia Gagnon 15, Giovanni Latella 16, Claudio Marcocci 17, Jeffrey I Mechanick 18, Salvatore Minisola 19, René Rizzoli 20, Ferruccio Santini 21, Joseph L Shaker 22, Christopher Sempos 23, Fabio Massimo Ulivieri 2, Jyrki K Virtanen 24, Nicola Napoli 25 26, Anne L Schafer 27, John P Bilezikian 28

Bariatric surgery is associated with a postoperative reduction of 25(OH) vitamin D levels (25(OH)D) and with skeletal complications. Currently, guidelines for 25(OH)D assessment and vitamin D supplementation in bariatric patients, pre- and post-surgery, are still lacking. The aim of this work is to analyse systematically the published experience on 25(OH)D status and vitamin D supplementation, pre- and post-surgery, and to propose, on this basis, recommendations for management.
Preoperatively, 18 studies including 2,869 patients were evaluated. Prevalence of vitamin D insufficiency as defined by 25(OH)D < 30 ng/mL (75 nmol/L) was 85%, whereas when defined by 25(OH)D < 20 ng/mL (50 nmol/L) was 57%. The median preoperative 25(OH)D level was 19.75 ng/mL.
After surgery, 39 studies including 5,296 patients were analysed and among those undergoing either malabsorptive or restrictive procedures, a lower rate of vitamin D insufficiency and higher 25(OH)D levels postoperatively were observed in patients treated with high-dose oral vitamin D supplementation, defined as ≥ 2,000 IU/daily (mostly D3-formulation), compared with low-doses (< 2,000 IU/daily).
Our recommendations based on this systematic review and meta-analysis should help clinical practice in the assessment and management of vitamin D status before and after bariatric surgery. Assessment of vitamin D should be performed pre- and postoperatively in all patients undergoing bariatric surgery. Regardless of the type of procedure, high-dose supplementation is recommended in patients after bariatric surgery.
 Download the PDF from VitaminDWiki


Note: Best to have Vitamin D loading dose before or after any surgery

A Loading dose will provide benefit in weeks instead of 5+ months
Probably also need Gut-Friendly Vitamin D as there is poor gut absorption after bariatric surgery


The Effect of Vitamin D Adequacy on Thyroid Hormones and Inflammatory Markers after Bariatric Surgery - 2023

Hormones and Inflammatory Markers after Bariatric Surgery. Metabolites 2023,13, 603. https://doi.org/10.3390/ metabo13050603

Roberta França h2, Adryana Cordeiro cordeiroadryana at gmail.com, Silvia Elaine Pereira 2,:3, Carlos José Saboya 3 and Andrea Ramalho 2,4

  1. Faculty of Medicine, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-598, Brazil
  2. Micronutrients Research Center (NPqM), Institute of Nutrition, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil
  3. Multidisciplinary Center of Bariatric and Metabolic Surgery Carlos Saboya, Rio de Janeiro 22280-020, Brazil
  4. Department of Social Applied Nutrition, Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil

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Vitamin D status affects the clinical and corporal outcomes of postoperative patients who undergo a Roux-en-Y gastric bypass (RYGB). The aim of this study was to evaluate the effect of adequate vitamin D serum concentrations on thyroid hormones, body weight, blood cell count, and inflammation after an RYGB. A prospective observational study was conducted with eighty-eight patients from whom we collected blood samples before and 6 months after surgery to evaluate their levels of 25-hydroxyvitamin D 25(OH)D, thyroid hormones, and their blood cell count. Their body weight, body mass index (BMI), total weight loss, and excess weight loss were also evaluated 6 and 12 months after surgery. After 6 months, 58% of the patients achieved an adequate vitamin D nutritional status. Patients in the adequate group showed a decrease in the concentration of thyroid-stimulating hormone (TSH) (3.01 vs. 2.22 pUI/mL, p = 0.017) with lower concentrations than the inadequate group at 6 months (2.22 vs. 2.84 pUI/mL, p = 0.020). Six months after surgery, the group with vitamin D adequacy showed a significantly lower BMI compared with the inadequate group at 12 months (31.51 vs. 35.04 kg/m2, p = 0.018). An adequate vitamin D nutritional status seems to favor a significant improvement in one's thyroid hormone levels, immune inflammatory profile, and weight loss performance after an RYGB.
 Download the PDF from VitaminDWiki


Obesity is associated with low Vitamin D (and treated by D as well) – Aug 2019 has the following

Fast weight loss by Obese Adults: Summary of the data as of Sept 2019
1) 50,000 IU Vitamin D weekly for at least 6 months
   If gut problems, should use a gut-friendly form of vitamin D
2) Add calorie restriction diet and light exercise after ~2 months*
   * Vitamin D levels must be above 30ng/ml to help with weight loss
   * Start losing weight 2 months sooner if take a 50,000 IU daily for a week
3) More weight loss if also add Magnesium or cofactors
   30% Improved Vitamin D response with Magnesium - a Vitamin D Cofactor
   Note: Magnesium reduces weight loss by itself as well
   20% improved vitamin D response if also add Omega-3 a Vitamin D Cofactor
  Note: Omega-3 reduces weight loss by itself as well
4) More weight loss if also improve activation of Vitamin D Receptor
   Vitamin D Receptor activator: 0-30% improved Vitamin D response
   Obesity 1.5 X more likely if poor Vitamin D Receptor – meta-analysis Nov 2019
Update Dec 2019 - Dr. Greger plant-based eating (not diet) for both weight loss and health.
  His book does not mention Vitamin D nor Adenovirus


Risk of divorce increases 2X in the 5 years after Bariatric Surgery - Nov 2023

 Download the Bloomberg PDF from VitaminDWiki


VitaminDWiki – Overview Obesity and Vitamin D contains

Obese need more Vitamin D
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  • Normal weight     Obese     (50 ng = 125 nanomole)

Click here for 2014 study


VitaminDWiki – People with with poor digestion need gut-friendly Vitamin D

Gut-friendly, Sublingual, injection, topical, UV, sunshine

Getting Vitamin D into your body has the following chart
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Getting Vitamin D into your body also has the following
If poorly functioning gut
Bio-D-Mulsion Forte – especially made for those with poorly functioning guts, or perhaps lacking gallbladder
Sublingual – goes directly into the bloodstream
Fat-soluble Vitamins go thru the slow lymph system
   you can make your own sublingual by dissolving Vitamin D in water or use nano form
Oil: 1 drop typically contains 400 IU, 1,000 IU, or 4,000 IU, typically not taste good
Topical – goes directly into the bloodstream. Put oil on your skin, Use Aloe vera cream with Vitamin D, or make your own
Vaginal – goes directly into the bloodstream. Prescription-only?
Bio-Tech might be usefulit is also water-soluble
Vitamin D sprayed inside cheeks (buccal spray) - several studies
    and, those people with malabsorption problems had a larger response to spray
Inject Vitamin D quarterly into muscle, into vein, or perhaps into body cavity if quickly needed
Nanoparticles could be used to increase vitamin D getting to the gut – Oct 2015
Poor guts need different forms of vitamin D has the following
Guesses of Vitamin D response if poor gut

Bio FormSpeedDuration
10Injection ($$$)
or Calcidiol or Calcitriol
D - Slow
C -Fast
Long
10 Sun/UVBSlowLong
10Topical
(skin patch/cream, vagina)
Slow
Fast nano
Normal
9Nanoemulsion -mucosal
perhaps activates VDR
FastNormal
9?Inhaled (future)FastNormal
8Bio-D-Mulsion ForteNormalNormal
6Water soluble (Bio-Tech)NormalNormal
4Sublingual/spray
(some goes into gut)
FastNormal
3Coconut oil basedSlowNormal
2Food (salmon etc.)SlowNormal
2Olive oil based (majority)SlowNormal

10= best bioavailable, 0 = worst, guesses have a range of +-2
Speed: Fast ~2-6 hours, Slow ~10-30 hours
Duration: Long ~3-6 months, Normal = ~2 months


Bariatic Surgery reduces the risk of some Cancers - March 2024

Bariatric Surgery and Longitudinal Cancer Risk Jan 2024
doi:10.1001/jamasurg.2023.5809 PDF is behind a paywall
Discussed at MD Edge

Decreased Breast Cancer (vs those who remained obese)
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Potential biases of the study
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Study can be viewed on from DeepDyve You can try their excellent system for free for a few weeks.

Attached files

ID Name Comment Uploaded Size Downloads
20912 Biases.png admin 03 Mar, 2024 117.17 Kb 80
20911 Surgery decrease BC.png admin 03 Mar, 2024 136.21 Kb 79
20369 BS then divorce.pdf admin 16 Nov, 2023 56.42 Kb 69
20332 BS.png admin 02 Nov, 2023 320.31 Kb 177
20068 Bariatric Surgery meta_CompressPdf.pdf admin 04 Sep, 2023 1.05 Mb 128
19525 Bariatric graph.jpg admin 30 Apr, 2023 24.83 Kb 266
19524 Bariatric weight.jpg admin 30 Apr, 2023 46.73 Kb 267
19523 Bariatric Surgery FG_CompressPdf.pdf admin 30 Apr, 2023 377.54 Kb 193