Periodontitis reduced by Vitamin D - many studies

---

26+ VitaminDWiki pages with PERIODON... in the title

This list is automatically updated

---

3% less likely to get Peridontitis for every 1 ng more vitamin D - April 2021

Association between Periodontitis and Vitamin D Status: A case-control study
Saudi Journal of Biological Sciences https://doi.org/10.1016/j.sjbs.2021.04.006
AbdullahAli H. AlzahraniaRaed A.AlharbibMohammedSarhan A. AlzahranicMohammed A.SindidGhaliaShamlaneFaisal A.AlzahranifMohammad A.AlbanghaligAbdulmajeedAbdulghani A Sindih

Vitamin D deficiency and periodontitis are commonly prevalent among Saudi adults. However, the association between periodontitis and vitamin D status has not been well documented. This study aims to examine the association between periodontitis and vitamin D status among adults in the Albaha region of Saudi Arabia. A case-control study of 123 Saudi adults was conducted; 60 had severe or moderate periodontitis, and 63 were periodontally healthy. Data was collected by an online self-reported sociodemographic questionnaire. All participants then underwent a full periodontal examination. Blood samples were also provided to assess participants’ vitamin D statuses through serum levels of 25-hydroxyvitamin D (25(OH)D). A total of 60 cases and 63 controls matched for BMI (30.2 ± 4.86 kg/m2), age (40.01 ± 7.73 years), and sex (46.3% and 53.7% male and female, respectively) participated in the study. Mean levels of 25(OH)D were significantly lower in periodontitis participants than in controls (25.03 ± 8.55 ng/ml, 29.19 ± 12.82 ng/ml, p = 0.037, respectively).
Lower odds of periodontitis were detected per unit of 25(OH)D level (OR 0.964, 95% CI; 0.931-0.999, p = 0.043). In conclusion, periodontitis is significantly associated with deficient and insufficient levels of vitamin D among Saudi adults in the Albaha region. Future longitudinal research with a larger sample size may be suggested to confirm these results.
 Download the PDF from VitaminDWiki

---

Risk of COVID-19 death 8X more likely if have peridontitis - Feb 2021

NEW STUDY LINKS PERIODONTITIS AND COVID‐19 COMPLICATIONS
"...After adjusting for potential confounders, periodontitis was associated with COVID‐19 complication including

• death (OR = 8.81, 95% CI 1.00–77.7),
• ICU admission (OR = 3.54, 95% CI 1.39–9.05) and
• need for assisted ventilation (OR = 4.57, 95% CI 1.19–17.4)."

DOI: https://doi.org/10.1111/jcpe.13435 FREE PDF

---

Hypothesis: COVID-19 & Periodontitis: The cytokine connection - Nov 2020

https://doi.org/10.1016/j.mehy.2020.109908 FREE PDF

---

The Importance of Vitamin D for Periodontal Tissues - March 2021

 Download the PDF from VitaminDWiki

---

Vitamin D and Periodontitis (no conclusion) - meta-analysis Aug 2020

Vitamin D and Periodontitis: A Systematic Review and Meta-Analysis
Nutrients doi: 10.3390/nu12082177
Vanessa Machado,1,2,*† Sofia Lobo,1,† Luís Proença,3 José João Mendes,2 and João Botelho1,2

To explore the vitamin D levels of periodontitis patients in comparison with periodontally healthy ones, and to assess the influence of vitamin D supplementation as an adjunctive during nonsurgical periodontal treatment (NSPT). Five databases (Pubmed, Embase, Scholar, Web of Sciences, and Cochrane Library) were searched until May 2020. Mean difference (MD) meta-analysis with corresponding 95% confidence interval (95% CI) and sensitivity tests via meta-regression were used. We followed Strength of Recommendation Taxonomy (SORT) to appraise the strength and quality of the evidence. Sixteen articles were included, fourteen case-control and two intervention studies, all reporting 25-hydroxyvitamin D (25(OH)D) levels. Compared with the healthy controls, the circulating 25(OH)D levels were significantly lower in chronic periodontitis patients (pooled MD = −6.80, 95% CI: −10.59 to −3.02). Subgroup analysis revealed differences among 25(OH)D measurements, with liquid chromatography-mass spectrometry being the most homogeneous method (pooled MD = −2.05, 95% CI: −3.40 to −0.71). Salivary levels of 25(OH)D showed no differences between groups. Due to the low number of studies, conclusions on aggressive periodontitis and in the effect of vitamin D supplementation after NSPT were not possible to ascribe. Compared with healthy controls, 25(OH)D serum levels are significantly lower in chronic periodontitis patients, with an overall SORT A recommendation. Future studies are needed to clarify the effect of vitamin D supplementation and the biological mechanisms linking vitamin D to the periodontium.

---

See also VitaminDWiki

• Dental category listing has 105 items along with related searches
• Inflammation category listing has 164 items along with related searches
• Inflammation reduced by a single dose of Vitamin D (200,000 IU) – RCT Jan 2016
• Inflammation is associated with low vitamin D in at least 15 diseases – April 2020
• Note: The founder of VitaminDWiki put Topical Vitamin D daily on his inflammed gums, which became healthy in about 2 weeks
  • Topical vitamin D works wonders for a variety of skin conditions
  • Topical application appears to get >100X higher concentration to that portion of the skin than the same amount taken orally
• 26 health factors increase the risk of COVID-19 – all are proxies for low vitamin D
  • Peridontitis adds another - which might have the largest increase in COVID-19 risk factor

---

There have been 3740 visits to this page