Epigenetics - PDFs and links, with and without Vitamin D

Human Epigenetics: How Science Works - PDF of 2019 book

New textbook explains human epigenetics to undergraduates
Carlberg, Carsten, Molnár, Ferdinand, DOI 10.1007/978-3-030-22907-8
Chromatin
DNA Methylation
Histone Modifications|
Chromatin Modifying Proteins and RNAs
Embryogenesis and Cellular Differentiation
Population Epigenetics and Aging
Cancer Epigenetics
Neuroepigenetics
Nutritional Epigenetics
Epigenetics of Immune Function
Epigenome-Environment Interactions and Their Therapy
 Download the PDF from Sci-Hub via VitaminDWiki

Strangely, "Vitamin D" is not mentioned in his book even once

A few images from the book

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A few of Carlberg, Carsten Vitamin D Studies

• Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes – Sept 2019 Free PDF doi: 10.3389/fimmu.2019.02211
  • “Thus, the epigenome of human monocytes is at multiple levels sensitive to vitamin D”
• Vitamin D and evolution: Pharmacologic implications – Aug 2019 doi: 10.1016/j.bcp.2019.07.024
• Vitamin D Nutrigenomics - High, Medium, and Low Responders - March 2019 on VitaminDWiki

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VitaminDWiki pages with EPIGENETICS in title (15 as of Dec 2021)

This list is automatically updated

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Vitamin D: a Review of its Effects on Epigenetics and Gene Regulation – 2020

Folia Med (Plovdiv) . 2020 Dec 31;62(4):662-667. doi: 10.3897/folmed.62.e50204..
Violeta Snegarova 1, Darina Naydenova 2

Vitamin D is a secosteroid hormone with known beneficial effects on several body systems other than the musculoskeletal system. Both 25 dihydroxy vitamin D [25(OH)2D] and its active hormonal form, 1,25-dihydroxyvitamin D [1,25(OH)2D] are essential for hu-man physiological functions, including damping down inflammation and the excessive intracellular oxidative stresses. In the present study we set out to review all available literature on vitamin D and the role it plays in epigenetics and gene regulation. We searched the PubMed/Medline electronic database for studies published in the English language up to January 2020. The Medical Subject Headings (MeSH) database was searched with the keywords 'vitamin D', 'DNA methylation', 'nutritional supplements', 'epigenome' and 'pregnancy'. Observational studies, supplementation studies, and meta-analyses dealing with the effect of vitamin D on epigenetics and gene regula-tion were included in the review. The obtained information from the databases such as PubMed, Google Scholar, and ResearchGate was analysed and summarized.
We found that hypovitaminosis D increases the incidence and severity of several age-related common diseases such as the oxidative stress-associated metabolic disorders.
These include

• obesity,
• insulin resistance,
• type 2 diabetes,
• hypertension,
• pregnancy complications,
• memory disorders,
• osteoporosis,
• autoimmune diseases,
• certain cancers, and
• systemic inflammatory diseases.

New understandings of vitamin D-related advances in metabolomics, transcriptomics, epigenetics, in relation to its ability to control oxidative stress in conjunction with micronutrients, vitamins, and antioxidants, following normalization of serum 25(OH)D and tissue 1,25(OH)2D concentra-tions, are likely to promise better cost-effective clinical outcomes in humans. There is a strong reciprocity between the vitamin D system and epigenetic mechanisms. The vitamin D system is, on the one hand regulated by epigenetic mechanisms and, on the other hand, is involved in regulating epigenetic events.
 Download the PDF from VitaminDWiki

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Restoring Vitamin D levels restored ~2 years to epigenetic life indictors - Dec 2021

People who had low vitamin D and supplemented so as to get >20 ng of vitamin D restored ther epigenitic indictors by ~1 years = same as the level of those who initially has > 20 ng of vitamin D. Study does not indicate Vitamin D dose size.
 Download the PDF preprint from VitaminDWiki

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Some Epigenetic and Vitamin D items on the web - Dec 2019

• Vitamin D status and epigenetic-based mortality risk score: strong independent and joint prediction of all-cause mortality in a population-based cohort study
  •  Download the June 2018 PDF from VitaminDWiki
• Vitamin D and the epigenome - April 2014  Download the PDF from VitaminDWiki
• Genetic and epigenetic factors influencing vitamin D status - October 2017 https://doi.org/10.1002/jcp.26216
  • "The aim of current review was to provide an overview of the possible value of loci associated to vitamin D metabolism, catabolism, and transport as well epigenetic modification and environmental factors influencing vitamin D status."
• Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis
  • March 2017  Download the PDF from VitaminDWiki
  • Vitamin D, Testosterone, Epigenetics and Pain an Evolving Concept of Neurosignaling, Neuroplasticity and Homeostasis - Dec 2017
  •  Download the PDF from Research Gate vis VitaminDWiki
• A Super Brief and Basic Explanation of Epigenetics for Total Beginners July 2018
• Wikipedia

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