Pivotal role of Boron supplementation on bone health - Dec 2020

Pivotal role of boron supplementation on bone health: A narrative review
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Pivotal role of boron supplementation on bone health: A narrative review

Journal of Trace Elements in Medicine and Biology Vol 62, Dec 2020, https://doi.org/10.1016/j.jtemb.2020.126577
Mariangela Rondanelli a b, Milena Anna Faliva c, Gabriella Peroni c, Vittoria Infantino b, Clara Gasparri c, Giancarlo Iannello d, Simone Perna e, Antonella Riva f, Giovanna Petrangolini f, Alice Tartara c

Table of Contents

Background
Boron is a trace element that plays an important role in numerous biological functions, including calcium metabolism, growth and maintenance of bone tissue. However, there are still no precise indications regarding a possible role of boron supplementation, and its amount of supplementation, to maintain bone health. So the aim of this narrative review was to consider the state of the art on the effectiveness of boron supplementation (alone or with other micronutrients) on growth and maintenance of bone in humans through control of calcium, vitamin D and sex steroid hormone metabolism in order to suggest a daily dosage of boron supplementation.

Main findings
This review included 11 eligible studies: 7 regarding the supplementation with boron alone and 4 regarding supplementation with boron and other nutrients. Despite the number of studies considered being low, the number of subjects studied is high (594) and the results are interesting.

Conclusions
The studies considered in this narrative review have evaluated the positive effectiveness on bone, in humans, through control of calcium, vitamin D and sex steroid hormone metabolism, considering a dietary supplementation of 3 mg/day of boron (alone or with other nutrients); this supplementation is demonstrably useful to support bone health (in order to prevent and maintain adequate bone mineral density), also considering the daily dose of 3 mg is much lower than the Upper Level indicated by EFSA in the daily dose of 10 mg.
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There are 30 Boron studies on this page and 36 additional Boron pages in VitaminDWiki

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20 recently changed items in (Vitamin D and Boron category

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Id	Page	Hits	Last modification	Creator	Categories
10392	World's Top Authors in Vitamin D, VDR, Vitamin K, Omega-3, etc - Jan 2019	4008	13 Dec, 2021 12:25	admin	Vitamin D and Vitamin K Vitamin D and Boron Vitamin D and Omega-3 Vitamin D Receptor Zinc Iodine
6743	Vitamin D Cofactors in a nutshell	106320	02 Jun, 2025 14:45	admin	Supplement Vitamin D and Calcium Vitamin D and Magnesium Vitamin D and Vitamin K Vitamin D and Vitamin A Vitamin D and Boron Vitamin D and Omega-3 Vitamin D and Iron Zinc Iodine Vitamin B12 Resveratrol Curcumin Vitamin C Glutathione
7906	Vitamin D and Boron	100661	31 Jul, 2023 14:47	admin	Vitamin D and Boron Category
10293	The Physiological Role of Boron on Health – Nov 2018	6540	08 Nov, 2019 16:43	admin	Bone - Health Vitamin D and Boron
14698	Supplements taken by the founder of VitaminDWiki	9717	08 Jun, 2025 23:46	admin	Supplement Vitamin D and Magnesium Vitamin D and Vitamin K Vitamin D and Boron Zinc Iodine Vitamin B12 Resveratrol Curcumin Vitamin C Glutathione
7986	Rheumatoid arthritis and many other diseases associated with low Boron – 2012	16740	03 Dec, 2016 16:26	admin	Rheumatoid Arthritis Top news Vitamin D and Boron
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11120	Prostate cancer risk cut in half by consuming Boron-rich food or water	8017	03 Sep, 2019 16:03	admin	Cancer - Prostate Vitamin D and Boron
15102	Pivotal role of Boron supplementation on bone health - Dec 2020	1309	04 Mar, 2024 19:08	admin	Vitamin D and Boron
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3519	Need at least 1 mg of Boron daily – Oct 2011	5368	12 Jan, 2013 19:42	admin	Vitamin D and Boron
1270	Low cost cofactors for vitamin D	159093	31 Jul, 2023 14:30	admin	Vitamin D and Calcium Vitamin D and Magnesium Top news Vitamin D and Vitamin K Vitamin D and Vitamin A Vitamin D and Boron Vitamin D and Omega-3 Vitamin D and Iron Zinc
12018	Knee osteoarthritis: Vitamin D is the 4th best treatment – meta-analysis Oct 2020	12193	21 Oct, 2020 12:59	admin	Meta-analysis of Vitamin D Vitamin D and Boron Osteoarthritis
7995	Knee osteoarthritis strongly associated with low Boron – 2015	14998	21 Oct, 2020 13:42	admin	Bone - Health Vitamin D and Boron Osteoarthritis
2906	Importance of Boron in the diet – June 2012	5636	30 Oct, 2016 16:59	admin	Vitamin D and Boron
3638	How much vitamin D and other nutrients do I take	30481	11 Jun, 2016 09:49	admin	Vitamin D and Magnesium Top news Vitamin D and Boron Vitamin D and Omega-3 Zinc
9360	High vitamin D is associated with high Calcium and no Boron (in hair) – June 2017	10437	26 Feb, 2018 23:24	admin	Vitamin D and Calcium Vitamin D and Boron
2768	Healthy bones need: Calcium, Vitamin D, Magnesium, Silicon, Vitamin K, and Boron – 2012	29302	11 Aug, 2023 12:30	admin	Bone - Health Supplement Osteoporosis Vitamin D and Magnesium Vitamin D and Vitamin K Vitamin D and Boron Vitamin C
7932	Far fewer joint problems (Osteochondrosis) when Boron was added to diet (pigs)	8476	30 Oct, 2016 17:06	admin	Vitamin D and Boron Osteoarthritis
13493	Excellent reviews of supplements at ConsumerLab	6032	17 Oct, 2023 18:06	admin	Supplement Vitamin D and Calcium Vitamin D and Magnesium Vitamin D and Vitamin K Vitamin D and Vitamin A Vitamin D and Boron Vitamin D and Omega-3 Vitamin D and Iron Zinc Iodine Vitamin B12 Resveratrol Curcumin Vitamin C

Pivotal role of Boron supplementation on bone health - Dec 2020

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Pivotal role of Boron supplementation on bone health - Dec 2020

Pivotal role of boron supplementation on bone health: A narrative review

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20 recently changed items in (Vitamin D and Boron category

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