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Sang Yoon Lee, Hee Joon Ro, Sun G. Chung, Si Hyun Kang, Kyung Mook Seo, Don-Kyu Kim
Low Skeletal Muscle Mass in the Lower Limbs Is Independently Associated to Knee Osteoarthritis
www.plosone.org
www.plosone.org
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(analysis)Tj
3.3222 0 Td
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(public)Tj
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2.2054 0 Td
(KNHANES)Tj
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(and)Tj
1.7291 0 Td
(therefore)Tj
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(ethi-)Tj
-35.6312 -1.2982 Td
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(approval)Tj
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1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 524.9196 cm
BT
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1 TL
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6.926 0 Td
(data)Tj
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(serum)Tj
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(vitamin)Tj
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(calculated)Tj
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7.4999 0 0 6.6659 479.2818 499.3511 cm
BT
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1 TL
-0.0053 Tc
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(2)Tj
ET
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q
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(25\(OH\)D)Tj
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(radioimmunoass)Tj
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(WIZARD)Tj
4.1726 0 Td
(gamma-counter;)Tj
6.8655 0 Td
(PerkinElmer,)Tj
5.5444 0 Td
(Finland\))Tj
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-34.2933 -1.2983 Td
(24)Tj
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(hours)Tj
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4.337 0 Td
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(insufficiency)Tj
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(20)Tj
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(ng/mL)Tj
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4.1896 0 Td
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1.0261 0 Td
(the)Tj
1.4684 0 Td
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4.405 0 Td
(Society)Tj
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(clinical)Tj
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(practice)Tj
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(guideline)Tj
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(17)Tj
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(].)Tj
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q
1 j
1 J
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11.9999 0 0 11.9999 200.0125 416.4661 cm
BT
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1 TL
-0.0033 Tc
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2.5275 0 Td
(OA)Tj
1.6583 0 Td
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Q
q
1 j
1 J
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10 0 0 10 200.0125 399.4582 cm
BT
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1 TL
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1.7801 0 Td
(presence)Tj
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(participants)Tj
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3.4809 0 Td
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1.9219 0 Td
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(experi-)Tj
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(arthralgia)Tj
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1.474 0 Td
(knee)Tj
2.1089 0 Td
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0 Tc
1.389 0 Td
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-0.004 Tc
(1)Tj
1.4627 0 Td
(month)Tj
2.9253 0 Td
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(3)Tj
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3.5092 0 Td
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(joints)Tj
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1.4683 0 Td
(antero-posterior)Tj
6.7805 0 Td
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(lateral)Tj
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-35.0019 -1.3039 Td
(30)Tj
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1.0148 0 Td
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(flexion.)Tj
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1.7802 0 Td
(radiographic)Tj
5.3347 0 Td
(findings)Tj
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(relating)Tj
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2.1089 0 Td
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1.6498 0 Td
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-34.8092 -1.2983 Td
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(grading)Tj
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(musculoskeletal)Tj
6.565 0 Td
(radiologists)Tj
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4.8075 0 Td
(grades)Tj
-33.0687 -1.2982 Td
(accepted.)Tj
3.9174 0 Td
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2.6816 0 Td
(there)Tj
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1.6951 0 Td
(a)Tj
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(difference)Tj
4.2009 0 Td
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(one)Tj
1.7008 0 Td
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(between)Tj
3.5263 0 Td
(the)Tj
1.4684 0 Td
(two)Tj
1.7121 0 Td
(radiologists')Tj
5.0456 0 Td
(assessments,)Tj
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(the)Tj
1.4683 0 Td
(higher)Tj
2.8006 0 Td
(grade)Tj
2.4434 0 Td
(was)Tj
1.7008 0 Td
(accepted)Tj
3.6907 0 Td
([)Tj
0.83 0.64 0.02 0 k
(14)Tj
0 g
(].)Tj
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Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 294.9732 cm
BT
/F0 1 Tf
1 TL
-0.0033 Tc
0 0 Td
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2.4756 0 Td
(composition)Tj
5.4898 0 Td
(and)Tj
1.8661 0 Td
(physical)Tj
3.7843 0 Td
(activity)Tj
3.241 0 Td
(measurements)Tj
ET
Q
q
1 j
1 J
0 w
10 0 0 10 200.0125 278.022 cm
BT
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1 TL
-0.004 Tc
0 0 Td
(A)Tj
0.9014 0 Td
(DEXA)Tj
2.8629 0 Td
(\(DISCOVERY-W,)Tj
7.5798 0 Td
(Hologic,)Tj
3.634 0 Td
(MA\))Tj
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1.4684 0 Td
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5.244 0 Td
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3.5546 0 Td
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-34.7411 -1.3039 Td
(mass,)Tj
2.4207 0 Td
(lean)Tj
1.8709 0 Td
(mass,)Tj
2.4207 0 Td
(and)Tj
1.7292 0 Td
(bone)Tj
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(mineral)Tj
3.3335 0 Td
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3.1011 0 Td
(\(BMD\))Tj
3.1068 0 Td
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(measured)Tj
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1.1849 0 Td
(DEXA.)Tj
3.084 0 Td
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2.2904 0 Td
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1.2416 0 Td
(percent-)Tj
-34.2196 -1.2982 Td
(age)Tj
1.542 0 Td
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1.7008 0 Td
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3.2258 0 Td
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1.0148 0 Td
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1.4683 0 Td
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4.5467 0 Td
(of)Tj
1.0148 0 Td
(fat)Tj
1.2416 0 Td
(mass)Tj
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(of)Tj
1.0148 0 Td
(the)Tj
1.4683 0 Td
(whole)Tj
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(body)Tj
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1.7858 0 Td
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2.0013 0 Td
(femur)Tj
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(BMD)Tj
-34.8092 -1.2983 Td
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1.6951 0 Td
(selected)Tj
3.3505 0 Td
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1.9955 0 Td
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(18)Tj
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(].)Tj
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(appendicular)Tj
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(skeletal)Tj
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(muscle)Tj
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1.4683 0 Td
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(lower)Tj
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(limbs,)Tj
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(sar-)Tj
-35.3478 -1.2983 Td
(copenia)Tj
3.3391 0 Td
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1.7008 0 Td
(diagnosed)Tj
4.2803 0 Td
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(19)Tj
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1.8538 0 Td
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(cut-off)Tj
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(Korean)Tj
3.1805 0 Td
(\(SMI)Tj
2.2677 0 Td
(29.53%)Tj
3.1067 0 Td
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(23.20%)Tj
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1.7064 0 Td
(standard)Tj
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(deviations)Tj
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1.7291 0 Td
(healthy)Tj
3.1295 0 Td
(indi-)Tj
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(2039)Tj
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(4th)Tj
1.5193 0 Td
(KNHANES)Tj
4.8643 0 Td
([)Tj
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(20)Tj
0 g
(].)Tj
2.0749 0 Td
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1.7858 0 Td
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3.0388 0 Td
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1.7007 0 Td
(defined)Tj
3.2258 0 Td
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(a)Tj
0.652 0 Td
(BMI)Tj
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0 Tc
2.0353 0 Td
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-0.004 Tc
(27.5)Tj
2.6418 0 Td
(kg/m)Tj
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1 j
1 J
0 w
7.4999 0 0 6.6659 463.0677 152.4472 cm
BT
/F6 1 Tf
1 TL
-0.0053 Tc
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(2)Tj
ET
Q
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1 j
1 J
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BT
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1 TL
-0.004 Tc
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(,)Tj
0.4478 0 Td
(which)Tj
2.6476 0 Td
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(associated)Tj
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-34.8659 -1.3039 Td
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3.9969 0 Td
(mortality)Tj
3.9174 0 Td
(rates)Tj
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1.0375 0 Td
(Asians)Tj
2.8743 0 Td
([)Tj
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(21)Tj
0 g
(])Tj
1.8538 0 Td
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1.7291 0 Td
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4.4958 0 Td
(obesity)Tj
3.0387 0 Td
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(defined)Tj
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(the)Tj
1.4683 0 Td
(condition)Tj
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(which)Tj
2.6476 0 Td
(criteria)Tj
3.0784 0 Td
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1.0148 0 Td
(both)Tj
2.0579 0 Td
(obesity)Tj
3.0387 0 Td
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1.7292 0 Td
(sarcopenia)Tj
4.507 0 Td
(were)Tj
2.126 0 Td
(satisfied.)Tj
3.6737 0 Td
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1.7801 0 Td
(short)Tj
2.2846 0 Td
(version)Tj
3.1521 0 Td
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1.474 0 Td
(IPAQ)Tj
2.5455 0 Td
(in)Tj
-36.1244 -1.2983 Td
(Korea)Tj
2.6306 0 Td
(\(IPAQ-K\))Tj
4.2519 0 Td
([)Tj
0.83 0.64 0.02 0 k
(22)Tj
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(which)Tj
2.6532 0 Td
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(health-related)Tj
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(activity)Tj
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1.0318 0 Td
(populations,)Tj
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(was)Tj
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(used)Tj
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(to)Tj
1.0261 0 Td
(measure)Tj
3.583 0 Td
(each)Tj
2.0239 0 Td
(subject's)Tj
3.5943 0 Td
(current)Tj
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(expressed)Tj
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(total)Tj
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(metabolic)Tj
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