Poor Periodontal associated with low vitamin D in 65 percent of cross-sectional studies – review

Created March 2018

Vitamin D levels and risk for periodontal disease: A systematic review

Journal of Periodontal Research, First published: 1 March 2018, DOI: 10.1111/jre.12531

J. P. N. S. Pinto, J. Goergen, F. W. M. G. Muniz, A. N. Haas alexnhaas@gmail.com

65% does not seem possible with 13 studies 8 / 13 = 61.5 %,     9 / 13 = 69 % --- 1. Vitamin D helps the mouth in many ways – VitaminDWiki * Dental implant failure 4 times more likely if low vitamin D (not statistically significant) – Sept 2016 * Periodontal disease 1.5 times more likely if low vitamin D – Sept 2016 * Chronic Periodontitis 9.6 times more likely if smoke and have poor Vitamin D Receptor – Aug 2016 * Tooth loss reduction by 15 percent associated with 10 ng higher vitamin D – May 2014 * UVB added in classroom reduced cavities, increased height, increased academics. Etc * * Dental category listing has items along with related searches** 1. Intervention AND Dental {category} 1. Pages listed in BOTH Dental and Infants {category} --- 1. Personal note by founder of VitaminDWiki I have been whitening my teeth with a mixture of powders which I make up: Vitamin D + Charcole + Bentonite Clay. Seems to help both my teeth and gums. Last year I had experimented with making a Vitamin D mouthwash as a quick way of getting Vitamin D into my body.

Objective

To evaluate the existing evidence supporting or refuting the following questions:

  • (i) Do patients with lower vitamin D levels have higher risk for periodontal disease?

  • (ii) Are periodontal treatment outcomes improved by the adjuvant supplementation of vitamin D or by elevated serum vitamin D levels?

Material and Methods

MEDLINE, SCOPUS, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched up to September 2017. Studies were included if they had measured serum vitamin D levels or vitamin D intake and any periodontal parameter.

Results

Overall, 27 studies were included (

  • 13 cross-sectional studies ,

  • 6 case-control studies,

  • 5 cohort studies,

  • 2 randomized clinical trials and

  • 1 case series study).

    Sixty-five percent of the cross-sectional studies reported significant associations between low vitamin D levels and poor periodontal parameters.

None of the observational longitudinal studies found that periodontal disease progression could be attributed to lower vitamin D levels.

No interventional studies that evaluated the use of vitamin D supplementation as a solely adjuvant to periodontal treatment was found.

No meta-analysis was performed due to high variability across studies.

Conclusion

The data to support or refute the association between vitamin D levels and periodontal disease are inconclusive at the moment. More rigorously designed longitudinal studies with standardized definitions of periodontal disease and vitamin D are necessary.

Tags: Dental