GLP-1- NOT use just before or while pregnant - lack of safety data Nov 2026

American College of Obstetricians and Gynecologists

Prepregnancy

Obstetrician–gynecologists and other health care professionals should advise their patients about the current lack of sufficient safety data regarding GLP-1RA use in pregnancy and to consider discontinuation 1–2 months before conception.

Pregnancy

Obstetrician–gynecologists and other health care professionals should advise against the use of GLP-1RAs during pregnancy.

Use of these medications during pregnancy could result in insufficient intake of vitamins and minerals essential to pregnancy, such as vitamins A, B1, B12, C, D, E, and K, as well as iron, calcium, magnesium, and zinc.

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