COVID infections/vaccinations increase turbo-cancers, journal was cyberattacked
COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms
Oncotarget Dec 2025
Charlotte Kuperwasser1,2 and Wafik S. El-Deiry3,4,5
A growing number of peer-reviewed publications have reported diverse cancer types appearing in temporal association with COVID-19 vaccination or infection. To characterize the nature and scope of these reports, a systematic literature search from January 2020 to October 2025 was conducted based on specified eligibility criteria.
A total of 69 publications met inclusion criteria: 66 article-level reports describing 333 patients across 27 countries, 2 retrospective population-level investigations (Italy: ~300,000 cohort, and Korea: ~8.4 million cohort) quantified cancer incidence and mortality trends among vaccinated populations, and one longitudinal analysis of ~1.3 million US military service members spanning the pre-pandemic through postpandemic periods.
Most of the studies documented hematologic malignancies (non-Hodgkin's lymphomas, cutaneous lymphomas, leukemias), solid tumors (breast, lung, melanoma, sarcoma, pancreatic cancer, and glioblastoma), and virus-associated cancers (Kaposi and Merkel cell carcinoma).
Across reports, several recurrent themes emerged:
- (1) unusually rapid progression, recurrence, or reactivation of preexisting indolent or controlled disease,
- (2) atypical or localized histopathologic findings, including involvement of vaccine injection sites or regional lymph nodes, and
- (3) proposed immunologic links between acute infection or vaccination and tumor dormancy, immune escape, or microenvironmental shifts.
The predominance of case-level observations and early population-level data demonstrates an early phase of potential safety-signal detection. These findings underscore the need for rigorous epidemiologic, longitudinal, clinical, histopathological, forensic, and mechanistic studies to assess whether and under what conditions COVID-19 vaccination or infection may be linked with cancer.
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