Cluster Headache update ( 80-100 ng vitamin D, etc) video Dec 2025
Vitamin D3 Anti-Inflammatory Regimen for Cluster Headache Prevention. A 2025 Update & Reflection
Summary by AI Studio
[00:00] Overview of the Regimen: Developed by Pete Batcheller (a retired Navy Fighter Pilot), this protocol uses high-dose Vitamin D3 and specific co-factors to reduce systemic inflammation.[1] It is reported to have an 80% success rate in significantly reducing or eliminating cluster headache attacks.[3][4]
[04:30] Target 25(OH)D Serum Levels: The 2025 update emphasizes reaching and maintaining a serum 25(OH)D level of 80–100 ng/mL (200–250 nmol/L). This range is considered the "therapeutic window" for neurological and anti-inflammatory benefits, which is significantly higher than standard lab "normal" ranges.
[10:15] Essential Co-factors: Vitamin D3 cannot work effectively alone; the regimen requires co-factors including Magnesium (critical for D3 metabolism), Vitamin K2 (to prevent arterial calcification), Omega-3 fish oil (for inflammation), Zinc, Boron, and Vitamin A (Retinol).
[18:45] The 2025 "Full Monty" Update: For those who do not respond to Vitamin D3 alone, the update introduces the "Antihistamine Full Monty." This involves adding specific H1 and H2 blockers (like Cetirizine and Famotidine) to address histamine-induced inflammation that may be triggering the "Beast" (cluster headaches).
[25:20] Safety and Long-Term Reflection: Reflection on a decade of use shows the regimen is generally safer and more cost-effective than traditional preventatives like Verapamil or CGRP monoclonal antibodies. 2025 data from similar high-dose D3 therapies (e.g., for psoriasis) reinforces the long-term safety profile when co-factors are managed.
[32:10] Gut Microbiome and Inflammation: The latest insights suggest a link between CH, gut health, and the microbiome.[5] The regimen's anti-inflammatory action may be partly due to its ability to modulate the gut-brain axis and restore microbial balance.
[38:55] Importance of Physician Collaboration: The update stresses that while the regimen is patient-led, it should be done under the guidance of a physician with regular blood testing to monitor 25(OH)D and calcium levels to prevent toxicity.
Key Insight from Glasp/Community: Recent community discussions highlight that many users find relief within as little as one week of starting the loading dose, but emphasize that skipping co-factors (especially magnesium) is the most common reason for protocol failure. Some patients also use the regimen alongside psilocybin or other alternative treatments for a synergistic effect (Source: vitamindregimen.com).
More information at VitaminDRegimen
Liposomal Glutathione might fight both migraine and cluster headaches Perplexity AI Dec 2025
- Chronic health problems and Vitamin D, Glutathione, Omega-3, or Magnesium
- Glutathione is often better than Vitamin D in fighting many toxins
- Glutathione should improve response to Vitamin D
- Glutathione improves Vitamin D in 9 ways many of which improve the response to vitamin D
Related in VitaminDWiki
- Cluster Headaches treated by high-dose Vitamin D, etc. (interview and transcript) 2022 interview
- Migraine headaches treated by Vitamin D – meta-analysis
- Acute Migraine 35 times more likely if low Magnesium levels
- Comparing High-dose vitamin D therapies (Omega-3, K2, Mg and B vitamins are common co-factors)
- Liposomal Gluthathione proven to fight T2D, Oxidative Stress, NAFLD, RA, HIV, PD, Autism, RSV, etc
| Dr. Coimbra books 2018 2016 |
Dr. Somerville Optimal Dose |
Dr. Gominak | Mr. Batcheller | Dr. Bredsen End of Alz. |
|
| Health problem | Multiple Sclerosis autoimmune, PD |
sleep, flu, pain, obesity, etc. |
Sleep | Cluster, Migraine Headaches |
Alzheimer's Park. being added |
| Number of people (2019) |
30,000 by 2022 |
5,000 | 5,000 | 9,000 (2024) |
>5,000 (2020) |
| Vitamin D target | PTH is target typ: 150ng |
100-140+ ng | 60-80 ng | PTH is target typ: 80 ng |
40-60 ng |
| Vitamin D daily dose (K = 1,000 IU) |
20K - 200K 1,000 IU/kg |
30K | 2K + monthly test increasing dose until goal |
4K - 40K 110 IU/kg |
? |
| Omega-3 ✻ | O-3 | O-3 | - - - | O-3 | O-3 |
| Magnesium ✻ | Mg | Mg | - - - | Mg (400 mg) | - |
| Vitamin K2 | K2 (no longer?) | K2 | - - - | K2 | - |
| Vitamin B... | B2, B9, B12 | B3 | B50-B100 3 months |
B50 | B12 |
| Zinc ✻ | Zn | - - - | Zn | - | |
| Boron ✻ ? | B | - - - | B | - | |
| Calcium Minimize rock-based Ca |
Decrease Ca | - - - | Ca | - | |
| Vitamin A avoid extremes |
avoid A | avoid A | - - - | A | - |
| Other | Choline Selenium Co-Q 10 |
- - - | Co-Q 10 | - | |
| Loading dose Days instead of months |
- - - | - - - | - - - | Loading "Cluster Balm" |
- |