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Winter increase in death rate by 25 percent is probably due to low UVB, Vitamin D – Jan 2017

Seasonal variations of U.S. mortality rates: Roles of solar ultraviolet-B doses, vitamin D, gene expression, and infections.

J Steroid Biochem Mol Biol. 2017 Jan 11. pii: S0960-0760(17)30003-1. doi: 10.1016/j.jsbmb.2017.01.003. [Epub ahead of print]
Grant WB1, Bhattoa HP2, Boucher BJ3.
1Sunlight, Nutrition, and Health Research Center, PO Box 641603, San Francisco, CA, 94164-1603 USA. Electronic address: wbgrant at infionline.net.
2Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Nagyerdei blvd 98, Debrecen, H-4032, Hungary.
3The Blizard Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.

Death rates in the U.S. show a pronounced seasonality. The broad seasonal variation shows about 25% higher death rates in winter than in summer with an additional few percent increase associated with the Christmas and New Year's holidays.
A pronounced increase in death rates also starts in mid-September, shortly after the school year begins.
The causes of death with large contributions to the observed seasonality include diseases of the

  • circulatory system; the
  • respiratory system; the
  • digestive system; and
  • endocrine, nutritional, and metabolic diseases.

Researchers have identified several factors showing seasonal variation that could possibly explain the seasonal variations in mortality rate.
These factors include

  • seasonal variations in solar ultraviolet-B(UVB) doses and serum 25-hydroxyvitamin D [25(OH)D] concentrations,
  • gene expression,
  • ambient temperature and humidity,
  • UVB effects on environmental pathogen load,
  • environmental pollutants and allergens, and
  • photoperiod (or length of day).

The factors with the strongest support in this analysis are

  • seasonal variations in solar UVB doses and
  • 25(OH)D concentrations.

In the U.S., population mean 25(OH)D concentrations range from 21ng/mL in March to 28ng/mL in August. Measures to ensure that all people had 25(OH)D concentrations >36ng/mL year round would probably reduce death rates significantly.

KEYWORDS:
Cardiovascular disease; Gene expression; Mortality rate; Respiratory tract infections; Season; Temperature; Vitamin D

PMID: 28088363 DOI: 10.1016/j.jsbmb.2017.01.003 Publisher wants $36 for the PDF


See also VitaminDWiki

Vitamin D UK 45 year olds Average vitamin D levels in UK vary with season: 14 ng to 29 ng
Image
Dark gray = 45 year-old MEN, light gray = 45 year-old WOMEN

UV varies a ot more with season at high latitudes
in wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=1660
This chart might impliy that the amount of change in seasonal death rate would vary with latitude
Perhaps 35% in Northern Canada, 5% in Tobago, vs 25% in the US

See also web

Image
 Download the PDF from VitaminDWiki

Attached files

ID Name Comment Uploaded Size Downloads
7679 Seasonal mortality Scotland 2000.pdf PDF admin 16 Jan, 2017 16:08 202.81 Kb 190
7678 Scotland Mortality.jpg admin 16 Jan, 2017 16:08 14.06 Kb 291
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