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Vitamin D should improve oral heath in adults (no intervention got to 30 ng) – Review April 2022


Br J Nutr. 2022 Apr 13;1-29. doi: 10.1017/S0007114522000964
Normaliza Ab Malik 1, Sa'ari Mohamad Yatim 2, Kasmawati Norhidayati Mokhtar 3, Siti Nur Rasyidah Md Ramli 4, Waruna Lakmal Dissanayaka 5, George Pelekos 6, Colman McGrath 7

This systematic review aimed to provide a synthesis of the evidence relating to how the provision of Vitamin D supplements influences oral health status. An electronic database search was performed across six databases using a standardised search strategy. The PICO framework was used to define the review question. The screening and selection followed PRISMA process. The quality of reporting was assessed using CONSORT guidelines, and the bias was assessed using the revised Cochrane tool RoB2. A total of 1812 studies were retrieved. 1427 studies were excluded due to unmet inclusion criteria. Full texts of 75 potential studies were retrieved and ultimately six studies met the inclusion criteria. There were limitations in the quality of reporting of studies (between 49% and 73%). 70% of the risk of bias items were in the low risks category. Vitamin D interventions varied with respect to dosage and duration. Qualitative syntheses identified significantly better oral health outcomes. Heterogeneity of study design, intervention and outcomes precluded quantitative synthesis. Few clinical trials investigated the effect of Vitamin D supplementation on oral health. There is considerable heterogeneity among studies interventions and oral health outcomes. Quality of reporting of studies have limitations and there is evidence of study biases.
Nonetheless, qualitative synthesis of the evidence suggest that Vitamin D supplements improve oral health outcomes, particularly periodontal health. Calcium may also play a significant role. Further high-quality trials are required of comparable Vitamin D supplements with similar oral health outcomes focus to inform quantitative synthesis of the evidence.
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Trials studied were old (<2018), short (often <2 months), used small doses (typically <1000 IU)

VitaminDWiki - Dental Intervention with Vitamin D

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VitaminDWiki - Dental category starts

105 Dental items

Some Dental studies

VitaminDWiki - [ages listed in BOTH Dental and Vitamin D Receptor
Poor VDR ==> less vitamin D getting to cells in mouth

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    • "The heritability of dental caries varies between 40 and 60% "

Created by admin. Last Modification: Monday April 18, 2022 22:24:28 GMT-0000 by admin. (Version 5)

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17453 ORAL HEALTH AND VITAMIN D.pdf PDF 2022 admin 18 Apr, 2022 22:12 1.05 Mb 76