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Vitamin D levels in Europe (some consume a lot of vitamin D) – Dec 2021

Influence of geographical latitude on vitamin D status: cross-sectional results from the BiomarCaRE consortium

Br J Nutr. 2021 Dec 22;1-27. doi: 10.1017/S0007114521005080
Viktor Oskarsson 1, Mats Eliasson 1, Veikko Salomaa 2, Jaakko Reinikainen 2, Satu Männistö 2, Luigi Palmieri 3, Chiara Donfrancesco 3, Susana Sans 4, Simona Costanzo 5, Giovanni de Gaetano 5, Licia Iacoviello 5 6, Giovanni Veronesi 6, Marco M Ferrario 6, Teresa Padro 7, Barbara Thorand 8, Cornelia Huth 8, Tanja Zeller 9 10, Stefan Blankenberg 9 10, Annie S Anderson 11, Hugh Tunstall-Pedoe 12, Kari Kuulasmaa 2, Stefan Söderberg 1, BiomarCaRE investigators

Countryng vs Sweden
Sweden 0.0
Germany -3.03
Finland -3.28
Italy -5.41
Scotland -6.54
Spain -9.28

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Even though sunlight is viewed as the most important determinant of 25-hydroxyvitamin D (25OHD) status, several European studies have observed higher 25(OH)D concentrations among north-Europeans than south-Europeans. We studied the association between geographical latitude (derived from ecological data) and 25(OH)D status in 6 European countries by using harmonized immunoassay data from 81,084 participants in the Biomarkers for Cardiovascular Risk Assessment in Europe (BiomarCaRE) project (male sex 48.9%; median age 50.8 years; examination period 1984 to 2014). Quantile regression models, adjusted for age, sex, decade and calendar week of sampling, and time from sampling to analysis, were used for between-country comparisons.

Up until the median percentile, the ordering of countries by 25(OH)D status (from highest to lowest) was as follows:

  1. Sweden (at 65.6 to 63.8 oN),
  2. Germany (at 48.4 oN),
  3. Finland (at 65.0 to 60.2 oN),
  4. Italy (at 45.6 to 41.5 oN),
  5. Scotland (at 58.2 to 55.1 oN), and
  6. Spain (at 41.5 oN).

From the 75th percentile and upwards, Finland had higher values than Germany.

As an example, using the Swedish cohort as comparator, the median 25(OH)D concentration was 3.03, 3.28, 5.41, 6.54, and 9.28 ng/mL lower in the German, Finnish, Italian, Scottish, and Spanish cohort, respectively (P-value < 0.001 for all comparisons).
The ordering of countries was highly consistent in subgroup analyses by sex, age, and decade and season of sampling.
In conclusion, we confirmed the previous observation of a north-to-south gradient of 25(OH)D status in Europe, with higher percentile values among north-Europeans than south-Europeans.

Created by admin. Last Modification: Wednesday December 22, 2021 17:12:25 GMT-0000 by admin. (Version 3)

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