A Review of the Role of Micronutrients and Bioactive Compounds on Immune System Supporting to Fight against the COVID-19 Disease
Foods. 2021 May 14;10(5):1088. doi: 10.3390/foods10051088
Montaña Cámara 1, María Cortes Sánchez-Mata 1, Virginia Fernández-Ruiz 1, Rosa María Cámara 1, Elena Cebadera 1, Laura Domínguez 1
- Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020
- COVID-19 risks reduced by Vitamin D, Magnesium, Zinc, Resveratrol, Omega-3, etc. (auto-updated) ))
COVID-19 treated by Vitamin D - studies, reports, videos
- As of Jan 31, 2024, the VitaminDWiki COVID page had: 19+ trial results, 37+ meta-analyses and reviews, Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, All 26 COVID risk factors are associated with low Vit D, Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 166 COVID Clinical Trials using Vitamin D (Aug 2023) Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries
Items in both categories Zinc and Virus:
- COVID was associated with low Vitamin D or Zinc – umbrella review Feb 2023
- 23 COVID mitigation strategies: at least 6 of which increase Vitamin D in cells - Sept 2022
- COVID and Zinc - many studies
- Surviving COVID with vitamins and minerals is not a myth – June 2022
- Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022
- How vitamins D, C, Zinc, and Selenium might fight COVID - Dec 2021
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- COVID-19 decreased risk if add Vitamin D, A, C, NAC, Se, Zn, or Omega-3 – Dec 2021
- COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021
- COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells)
- Vitamin D, C, A, and E, as well as Iron, Se, and Zinc each augment vaccine response – July 2021
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 and many other health problems – June 2021
- COVID-19 treatment outside of hospital – Vitamin D, zinc, etc. – May 2021
- Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- Zinc therapy for COVID-19 – Feb 2021
- COVID-19 alternative treatments - real-time database
- Overview of reviews of COVID-19 and vitamin D, etc. – April 2021
- COVID-19 what it is, prevention by Functional Nutrition doctor - Feb 2021
- Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020
- Zinc (which increases vitamin D in tissues) may both prevent and treat COVID-19
- COVID-19 possible therapies: Vitamin D, Selenium, Zinc, Vitamin C, Potassium, Resveratrol , etc.– Aug 5, 2020
- 7 reasons to think that Zinc should fight COVID-19 – July 2020
- Observations that Vitamin D, Zinc, and Selenium separately reduce COVID-19 – Aug 7, 2020
- Mild COVID-19 quickly treated by Zinc lozenges in 4 people – June 6, 2020
- Zinc, respiratory tract infections and COVID-19 – July 2020
- Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020
- Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018
- Loss of smell may be related to low Zinc or perhaps low vitamin D
- Dengue fever immune response and micronutrients (vitamins D, E, A, and Zinc, Iron, Chromium) – Nov 2015
- Overview Colds and flu and Vitamin D
Items in both categories Virus and Vitamin C:
- COVID appears to be treated by many antioxidants (Vitamins D, C, E, K, and Quercetin, Curcumin, etc) – Jan 2023
- COVID fought by the antioxidants: Vitamin D, Zinc, Vitamin C, and Selenium – Review Sept 2022
- COVID worse if lower Vitamin C, but not Vitamin D in this study – Aug 2022
- Surviving COVID with vitamins and minerals is not a myth – June 2022
- COVID treatment patent applied for - using Rutin, Vitamin D, Vitamin C, Magnesium, etc. – April 2022
- How vitamins A, B, C, D, E, F (Omega), K fight COVID - Feb 2022
- How vitamins D, C, Zinc, and Selenium might fight COVID - Dec 2021
- Vitamin C helps COVID-19 (IV and oral) – review of 12 studies Oct 2021
- COVID-19 decreased risk if add Vitamin D, A, C, NAC, Se, Zn, or Omega-3 – Dec 2021
- COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021
- Vitamin D, C, A, and E, as well as Iron, Se, and Zinc each augment vaccine response – July 2021
- COVID-19 treatment outside of hospital – Vitamin D, zinc, etc. – May 2021
- Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- Overview of reviews of COVID-19 and vitamin D, etc. – April 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020
- Vitamin C may treat COVID-19 (several studies)
- For COVID-19: Vitamin C use might cause kidney stones, but Vitamin D will not– Aug 8, 2020
- COVID-19 possible therapies: Vitamin D, Selenium, Zinc, Vitamin C, Potassium, Resveratrol , etc.– Aug 5, 2020
- Vitamin C IV, which treats Sepsis, also treats COVID-19 - May 2020
- Does vitamin D (and C) help with Covid-19 - May 2020
- Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020
- COVID-19 prompts awareness of deficiencies of Vitamin D, C and Magnesium - April 6 2020
- Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018
 Download the PDF from VitaminDWiki
Micronutrients are critical for an adequate function of the immune system and play a vital role in promoting health and nutritional well-being. The present work is aimed at reviewing (1) the role of micronutrients in helping the immune system to fight against the COVID-19 disease through the diet with food or food supplements and (2) the potential use of food health claims regarding immune function according to the European Food Safety Authority (EFSA) requirements. Till date, there are some health claims authorized by the European Commission that refer to the role of certain essential nutrients (vitamins B6, B9, B12, A, D, C, and Cu, Fe, Se) to contribute to the proper functioning of the immune system.
Vitamins D, C, Zn, and Se, have been thoroughly studied as a strategy to improve the immune system to fight against COVID-19 disease.
From all the micronutrients, Vitamin D is the one with more scientific evidence suggesting positive effects against COVID-19 disease as it is linked to a reduction of infection rates, as well as an improved outcomes in patients. To validate scientific evidence, different clinical trials are ongoing currently, with promising preliminary results although inconclusive yet.