High versus Moderate Dosage of Daily and Weekly Administration of Vitamin D Supplements in the Form of Oil Drop in Nursing Home Residents.
Journal of the College of Physicians and Surgeons -Pakistan : JCPSP [01 Aug 2018, 28(8):618-622], DOI: 10.29271/jcpsp.2018.08.618
Mol R 1 , Kansu AD 2 , Cebe T 2 , Yildiz S 1 , Butun VK 1 , Simsek B 2 , Cakatay U 3
|Daily 800 IU||Weekly 5,600 IU|
|Vitamin D at 26 weeks||27 ng||37 ng|
Perhaps the higher level was in part due to increased compliance with weekly dosing
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- Intervention - non daily category listing has
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1 pill every two weeks fights all of the following
Diabetes + Heart Failure + Chronic Pain + Depression + Autism + Breast Cancer + Colon Cancer + Prostate Cancer + Preeclampsia + Premature Birth + Falls + Cognitive Decline + Respiratory Tract Infection + Influenza + Tuberculosis + Chronic Obstructive Pulmonary Disease + Lupus + Inflammatory Bowel Syndrome + Urinary Tract Infection + Poor Sleep + Weight Loss + Growing Pain (22 problems)
To investigate the effectiveness of daily (800 IU), weekly-moderate (5600 IU) and weekly-high (8000 IU) supplementation of Vitamin D in nursing home residents. A descriptive study. Nursing Home, MEVA, Istanbul, Turkey, from July 2016 to July 2017.
Nursing home residents were divided into 3 groups for supplementation of Vitamin D: Daily Dose Group (DDG), Weekly Dose Group-moderate (WDG-moderate) and Weekly Dose Group-high (WDG-high). Blood and physical performance tests were done initially to obtain a baseline value and the tests were repeated at 13th and 26th weeks of supplementation. Statistical analysis was conducted only on patients who were able to complete the 6-month-long study.WDG-moderate (5600 IU/week) supplementation is found to be the most effective intervention in our study [25 (OH) D from 23.50 ±12.67 ng/mL to 37.38 ±14.42 ng/mL]. In WDG-moderate, the resulting Vitamin D level was found to reach near-optimum therapeutic levels. Only a limited increase was observed in 25 (OH) D level of DDG and WDG- high at the end of 26 weeks.
Weekly (5600 IU/week) moderate supplementation of Vitamin D could be more beneficial than weekly (8000/week) high supplementation among nursing home residents. Multi-drug use among nursing home residents may hinder the therapeutic efficiency of Vitamin D administration. Physical performance tests may fail to demonstrate increased performance in mobility after Vitamin D administration in nursing home residents.
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