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Vitamin D both reduces CVD directly and reduces metabolic problems that cause CVD – May 2023


The Role of Vitamin D in Reducing the Risk of Metabolic Disturbances That Cause Cardiovascular Diseases

J. Cardiovasc. Dev. Dis. 2023, 10(5), 209; https://doi.org/10.3390/jcdd10050209
by Ziad H. Al-Oanzi 1,*ORCID,Fawaz O. Alenazy 1ORCID,Hassan H. Alhassan 1ORCID,Yasir Alruwaili 1,Abdulaziz I. Alessa 2,Nouf B. Alfarm 2,Maha O. Alanazi 2 andSarah I. Alghofaili 2
1 Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia
2 Department of Pharmacy, Prince Sultan Cardiac Center, Riyadh 11159, Saudi Arabia

Among the most common problems facing public health today is a lack of vitamin D, which plays a role in the physiological processes of chronic illness conditions.
Vitamin D deficiency in metabolic disorders has primary effects on

  • osteoporosis,
  • obesity,
  • hypertension,
  • diabetes, and
  • cardiovascular disease (CVD).

Vitamin D acts as a “co-hormone” in the various tissues of the body, and it has been found that vitamin D receptors (VDR) are present on all cell types, suggesting that vitamin D has a wide range of effects on most cells.
Recently, there has been a surge in interest in assessing its roles. Vitamin D insufficiency increases the risk of diabetes because it lowers insulin sensitivity, and also raises the risk of obesity and CVD because of its effect on the body’s lipid profile, particularly in terms of the prevalence of dangerously high levels of low-density lipoproteins (LDL).
Furthermore, vitamin D insufficiency is often related to CVD and connected risk factors, highlighting the need to know vitamin D’s functions in relation to metabolic syndrome and related processes. Through looking at previous studies, this paper explains why vitamin D is important, how deficiency is related to risk factors for metabolic syndrome through different mechanisms, and how deficiency affects CVD.
 Download the PDF from VitaminDWiki


VitaminDwiki – Cardiovascular category contains

526 items In Cardiovascular category

Cardiovascular category is associated with other categories: Diabetes 31, Omega-3 31 , Vitamin K 25 , Intervention 22 . Mortality 20 , Skin - Dark 18 , Magnesium 17 , Calcium 14 , Hypertension 14 , Trauma and surgery 13 , Stroke 13 , Kidney 12 , Metabolic Syndrome 11 , Seniors 10 , Pregnancy 8 as of Aug 2022


Cholesterol, Statins


VitaminDwiki – Metabolic Syndrome contains

105 items

See also


Metabolic Syndrome Associations with 12 other categories

 Obesity 19;  Diabetes 15;  Cardiovascular 12;  Magnesium 8;  Seniors 8;  Women 5; 5;  Hypertension 5;  Intervention 5;  Omega-3 4;  Youth 4;  Meta-analysis 4


VitaminDWiki – Overview Diabetes and vitamin D contains

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 548 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

Number of articles in both categories of Diabetes and:

  • Dark Skin 24;   Intervention 56;   Meta-analysis 39;   Obesity 36;  Pregnancy 44;   T1 (child) 39;  Omega-3 11;  Vitamin D Receptor 24;  Genetics 13;  Magnesium 29    Click here to see details

Some Diabetes studies

50 ng of Vitamin D fights Diabetes

T1 Diabetes

Pre-Diabetes

Diabetes, Metabolic Syndrome and Magnesium - many studies
Diabetic Epidemic

  • Step back to 1994. Suppose an epidemic struck the United States, causing blindness, kidney failure, and leg amputations in steadily increasing numbers.
    Suppose that in less than a decade's time, the epidemic had victimized one out of every eight people
    That epidemic is real, and its name is diabetes, now the nation's sixth leading cause of death.
    Chart from the web (2018?)
    Image

VitaminDWiki – Diabetes category contains

548 items In Diabetes category   34+ Prediabetes studies   64+ Type 1 Diabetes studies

see also Overview Diabetes and vitamin D  Overview Metabolic Syndrome and vitamin D

Autoimmune category listing has 199 items along with related searches

VitaminDWiki – Overview Obesity and Vitamin D contains

See also: Weight loss and Vitamin D - many studies   Child Obesity and Vitamin D - many studies   Obesity, Virus, and Vitamin D - many studies
Obese need more Vitamin D
Image

  • Normal weight     Obese     (50 ng = 125 nanomole)

Click here for 2014 study


VutaminDWiki - Hypertension category contains

164 items in the category HYPERTENSION

see also
Overview Overview Hypertension and Vitamin D
Overview Cardiovascular and vitamin D
Overview Stroke and vitamin D
Incidence of 22 health problems related to vitamin D have doubled in a decade
Some interesting Hypertension studies


VitaminDWiki - The risk of 44+ diseases at least double with poor Vitamin D Receptor


VitaminDWiki - Vitamin D Receptor activation can be increased in 14 ways

Resveratrol,  Omega-3,  MagnesiumZinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise, Butyrate   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 14 known VDR activators

Attached files

ID Name Comment Uploaded Size Downloads
19598 Vit D MS CVD_CompressPdf.pdf admin 26 May, 2023 229.05 Kb 90