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UVB phototherapy (which increases Vitamin D and VDR) decreased risk of many heart and stroke problems – July 2020

Both Cardiovascular and Cerebrovascular Events are Decreased Following Long-term NB- UVB Phototherapy in Patients with Vitiligo: A Propensity-score Matching Analysis

Journal of the European Academy of Dermatology and Venereology doi: 10.1111/jdv.16830
Jung Min Bae, MD, PhD,1* Yoon-Seob Kim, MD,2* Eun Ho Choo, MD,3 Mi-Yeon Kim MD,4 Jun Young Lee, MD, PhD,5 Hyung-Ok Kim, MD, PhD,6 and Young Min Park, MD, PhD.5
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VitaminDWiki

This study is based on 3,000 Koreans following 10 years of UVB treatment

Items in both categories Vitamin D Receptor and UV are listed here:

Items in both categories Skin and UV are listed here:

Items in both categories Cardiovascular and UV are listed here:

Items in both categories Stroke and Vitamin D Receptor are listed here:

Vitamin D Receptor activation can be increased by any of: Resveratrol,  Omega-3,  MagnesiumZinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise,   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 12 known VDR activators


Cardiovascular category starts with the following

507 items In Cardiovascular category

Cardiovascular category is associated with other categories: Diabetes 31, Omega-3 31 , Vitamin K 25 , Intervention 22 . Mortality 20 , Skin - Dark 18 , Magnesium 17 , Calcium 14 , Hypertension 14 , Trauma and surgery 13 , Stroke 13 , Kidney 12 , Metabolic Syndrome 11 , Seniors 10 , Pregnancy 8 as of Aug 2022


Cholesterol, Statins

 Download the PDF from VitaminDWiki
Background: Systemic effects of long-term narrowband ultraviolet B (NB-UVB) phototherapy have not been well studied in vitiligo patients. An 11-year nationwide population-based retrospective cohort study was conducted using the Korean National Health Insurance claims database (2007-2017).

Objectives: To investigate the effects of long-term NB-UVB phototherapy on the risk of cardiovascular and cerebrovascular events in vitiligo patients.

Methods: This study included vitiligo patients with >100 phototherapy sessions (phototherapy group, n = 3,229) and <3 phototherapy sessions (no phototherapy group, n = 9,687), in which covariables with age, sex, insurance type, and comorbidities such as diabetes, hypertension, and hyperlipidemia were matched by 1:3 propensity score matching. The outcomes of interest were cardiovascular (ischemic heart disease and myocardial infarction) and cerebrovascular events (cerebrovascular infraction and hemorrhage). Cox proportional hazards models were used to assess the associations between NB-UVB phototherapy and each event.

Results: The risk of cardiovascular or cerebrovascular events was significantly decreased in the phototherapy group compared with the no phototherapy group (hazard ratio HR 0.637, 95% confidence interval CI 0.523-0.776). Subgroup analysis revealed that the risk of cardiovascular (HR 0.682, 95% CI 0.495-0.940) and cerebrovascular events (HR 0.601, 95% CI 0.470-0.769) were significantly lower in the phototherapy group than the no phototherapy group, respectively.

Conclusions: Our findings suggest that long-term NB-UVB phototherapy could decrease the risk of cardiovascular and cerebrovascular events in patients with vitiligo.


Created by admin. Last Modification: Wednesday July 29, 2020 01:55:28 GMT-0000 by admin. (Version 11)

Attached files

ID Name Comment Uploaded Size Downloads
14091 UVB phototherapy.jpg admin 29 Jul, 2020 168.47 Kb 523
14089 CVD, cerebrovas events, nb-UVB Bae.pdf admin 29 Jul, 2020 1.62 Mb 397