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Type I diabetes in dark skin children associated with low vitamin D if far from equator – Jan 2015

Vitamin D status and Type 1 diabetes in children: evaluation according to latitude and skin colour.

Minerva Pediatr. 2015 Jan 21. [Epub ahead of print]
Cadario F1, Prodam F, Savastio S, Monzani A, Balafrej A, Bellomo G, Bona G.
1 Division of Pediatrics, Department of Health Sciences, Università del Piemonte Orientale "AmedeoAvogadro", Novara, Italy - francesco.cadario at maggioreosp.novara.it.

VitaminDWiki Summary

Moroccan children
In Piedmont (latitude 45 degrees North)
T1D = 12 ng, no diabetes = 17 ng
In Morroco (latitude 32 degrees North)
no difference in vitamin D levels with/without diabetes

See also VitaminDWiki
T1 diabetes OR type1 diabetes in title 24 as of Jan 2015
Pages listed in BOTH the categories Diabetes and Dark Skin

AIM:
We aim to investigate vitamin D (25OHD) levels in children with or without type 1 diabetes (T1D) according to latitude and skin colour.

METHODS:
We compared 25OHD levels in children with T1D living in Piedmont, of Caucasian or Moroccan origin, with healthy control subjects matched for age and ethnicity. Data of resident children in Morocco, with and without T1D, were used for comparison.

RESULTS:
Caucasian (21.4±1.5 vs 24.0±0.5 ng/ml, p<0.05) and Moroccan children with T1D (12.0±2.6 vs 17.1±1.7 ng/ml, p<0.05) living in Piedmont had lower 25OHD levels than their counterparts without diabetes. Moroccan children living in Morocco with and without T1D had similar 25OHD levels. Vitamin D deficiency was associated with T1D in Caucasian and Moroccan children living in Piedmont (OR: 1.720, CI95% 1.034--2.860, p<0.03),

CONCLUSIONS: Lower vitamin D levels were associated with T1D in Piedmont. Further studies are necessary to explain a possible relationship between vitamin D and T1D.

PMID: 25604589

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