Tuberculosis -100 percent cure rate with 10,000 IU of vitamin D daily – RCT 2006

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The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion.

Acta Med Indones. 2006 Jan-Mar;38(1):3-5.
Nursyam EW1, Amin Z, Rumende CM.
1Departement of Internal Medicine, Faculty of Medicine, University of Indonesia-dr.Cipto Mangunkusumo Hospital, Jakarta.

AIM:
to compare the vitamin D group of pulmonary tuberculosis patients with a placebo group in terms of clinical improvement, nutritional status, sputum conversion, and radiological improvement.
METHODS:
sixty seven tuberculosis patient visiting the Pulmonary Clinic, of Cipto Mangunkusumo Hospital, Jakarta, from January 1st to August 31st, 2001 were included in this study. The subjects were randomised to receive vitamin D (0.25 mg/day) or placebo in a double blind method, during the 6th initial week of Tb treatment. The rate of sputum conversion, complete blood counts, blood chemistry as well as radiologic examination were evaluated.
RESULTS:
there were more male patients than females (39:28), 78.7% were in the productive age group, 71.6% had low nutritional status, 62.4% with low education level, and 67.2% with low income. One hundred percent of the vitamin D group and only 76.7% of the placebo group had sputum conversion. This difference is statistically significant (p=0.002).

CONCLUSION:
the sputum conversion had no correlation with the hemoglobin level, blood clotting time, calcium level, lymphocyte count, age, sex, and nutritional status. There were more subjects with radiological improvement in the vitamin D group.

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Cited 374 times in Google Scholar May 2023

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VitaminDwiki – Tuberculosis category contains

120 Tuberculosis studies:    13 RCT,   14 Meta-analyses,  8 Vitamin D Receptor

• TB patients had low Vitamin D and poor Vitamin D receptor – June 2019
• Tuberculosis recovery speeded up by single 450,000 IU dose of vitamin D – RCT Jan 2017
  • Receptor-related diseases respond especially well to high-dose Vitamin D
• Pulmonary Tuberculosis 2X more likely if poor Vitamin D Receptor (Mexico) – April 2018
• TB not prevented by a small amount of Vitamin D (2,000 IU daily average, Mongolia) – RCT July 2020
• Tuberculosis -100 percent cure rate with 10,000 IU of vitamin D daily – RCT 2006
• Latent Tuberculosis 44 percent less likely if Vitamin D more than 30 ng - 14th meta-analysis Jan 2022
• Tuberculosis (multi-drug resistant) was 13.4 X more likely to be quickly cleared with Vitamin D - Meta-analysis Feb 2019
• No tuberculosis if more than 80 ng of vitamin D (cattle) - Jan 2022

see also Overview Tuberculosis and Vitamin D    Breathing category
TB has been increasing

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Intervention studies of TB in VitaminDWiki