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Tuberculosis -100 percent cure rate with 10,000 IU of vitamin D daily – RCT 2006

The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion.

Acta Med Indones. 2006 Jan-Mar;38(1):3-5.
Nursyam EW1, Amin Z, Rumende CM.
1Departement of Internal Medicine, Faculty of Medicine, University of Indonesia-dr.Cipto Mangunkusumo Hospital, Jakarta.


AIM:
to compare the vitamin D group of pulmonary tuberculosis patients with a placebo group in terms of clinical improvement, nutritional status, sputum conversion, and radiological improvement.
METHODS:
sixty seven tuberculosis patient visiting the Pulmonary Clinic, of Cipto Mangunkusumo Hospital, Jakarta, from January 1st to August 31st, 2001 were included in this study. The subjects were randomised to receive vitamin D (0.25 mg/day) or placebo in a double blind method, during the 6th initial week of Tb treatment. The rate of sputum conversion, complete blood counts, blood chemistry as well as radiologic examination were evaluated.
RESULTS:
there were more male patients than females (39:28), 78.7% were in the productive age group, 71.6% had low nutritional status, 62.4% with low education level, and 67.2% with low income. One hundred percent of the vitamin D group and only 76.7% of the placebo group had sputum conversion. This difference is statistically significant (p=0.002).
CONCLUSION:
the sputum conversion had no correlation with the hemoglobin level, blood clotting time, calcium level, lymphocyte count, age, sex, and nutritional status. There were more subjects with radiological improvement in the vitamin D group.

PMID: 16479024

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Study cited 232 times in Google Scholar April 2016

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ID Name Comment Uploaded Size Downloads
6519 TB 2006.pdf PDF admin 03 Apr, 2016 23:17 39.61 Kb 254
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