A review on the effects of vitamin D attenuating ischemia reperfusion injuries
INTERNATIONAL JOURNAL OF FOOD PROPERTIES 2022, VOL. 25, NO. 1, 522-540 https://doi.org/10.1080/10942912.2022.2052084
Chaoran Chen a, Xiao Wan a*, Jia Shangb, Wunong Zhangc, and Zhenxing Xied
a institute of Nursing and Health, College of Nursing and Health, Henan University, Kaifeng, HN, China;
b Arts department, School of Kaifeng Culture and Tourism, Kaifeng, HN, China;
c College of Educational Sciences, Henan University, Kaifeng, HN, China;
d School of Basic Medical Sciences, Henan University, Kaifeng, HN, China
PDF Table of contents
Ischemia reperfusion (I/R) injuries occurred in many pathological and surgical processes (e.g. thrombolytic therapy, organ transplantation, aortic crossclamping, coronary angioplasty and cardiopulmonary bypass) and harmed multiple organs and tissues. Vitamin D is a well-known sterol hormone and a nutritional ingredient able to promote the deposit of calcium and regulate phosphorus metabolism in the body. In addition, vitamin D has therapeutic effects on some diseases (e.g. cardiovascular disease, diabetes, cancer, neurological diseases, multiple sclerosis and inflammation).
Studies showed that vitamin D3 was closely related with I/R injury occurrences in
- heart,
- brain,
- Spine,
- liver,
- kidney, and
- ovary.
The literature searching was conducted in PubMed, Embase, Cochrane Library, Web of Science, and SCOPUS from inception to 20 September 2021.
Data showed that supplements with vitamin D3 can remarkably attenuate I/R injuries. This paper reviewed recent progresses of vitamin D3 preventing I/R injuries in clinical investigations and animal tests to enlighten future studies.
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VitaminDWiki pages with ISCHEMIC (mainly stroke) in title (20 as of Oct 2022)
This list is automatically updated
Items found: 23
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Ischemic Stroke is 18% more likely if poor Vitamin D genes (unless take more Vitamin D) – Feb 2024 |
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21 Mar, 2024 |
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High Omega-3 reduced risk of Ischemic stroke by 18% - Dec 2023 |
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05 Jan, 2024 |
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Poor Acute Ischemic Stroke 4X more likely if low Vitamin D - Nov 2023 |
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11 Dec, 2023 |
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Elderly vaccinated for COVID were 2X more likely to die of ischemic stroke (2930 vs 1180 deaths)– Nov 2021 |
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22 Nov, 2021 |
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Poor Ischemic stroke outcome (END) 2.6 X worse if low vitamin D – March 2019 |
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26 Nov, 2019 |
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Death after Ischemic Stroke 2.5 X more likely if less than 10 ng of Vitamin D – May 2019 |
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02 May, 2019 |
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Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018 |
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29 Jun, 2018 |
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Ischemic Stroke risk reduced by 2.5 if have good level of vitamin D – meta-analysis Feb 2018 |
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28 Feb, 2018 |
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Vitamin D levels drop after ischemic stroke – Dec 2017 |
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20 Jan, 2018 |
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Ischemic stroke 17 X more likely if low vitamin D – April 2017 |
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13 Jan, 2018 |
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Large vessel Ischemic Stroke 13 X more likely if low vitamin D – Nov 2017 |
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04 Jan, 2018 |
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Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017 |
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27 Oct, 2017 |
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Ischemic stroke and low vitamin D – 3X higher risk of poor outcome, 6 X higher risk of a second stroke, Oct 2017 |
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04 Oct, 2017 |
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Better outcome following Ischemic stroke if injected with 600,000 IU of vitamin D – RCT Feb 2017 |
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01 Aug, 2017 |
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Death within 2 years of surviving an ischemic stroke 10X less likely if high vitamin D – July 2017 |
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01 Aug, 2017 |
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Risk of Ischemic Stroke doubles if take more than 1 gram of Calcium daily for years – May 2017 |
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20 May, 2017 |
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Ischemic Stroke risk best predicted by Vitamin D, including PTH improves the prediction – Feb 2017 |
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02 Mar, 2017 |
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Ischemic stroke 5 times more likely to recur if very low vitamin D – June 2016 |
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28 Jul, 2016 |
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Ischemic Stroke with low vitamin D resulted in larger lesions – May 2015 |
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11 Mar, 2016 |
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Vitamin D associated with 50 percent less ischemic stroke – meta-analysis Aug 2012 |
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12 Jul, 2015 |
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Ischemic Stroke 3X more likely if Vitamin D Receptor gene change (Fok 1) – Jan 2014 |
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29 Dec, 2014 |
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Ischemic stroke 2X more likely if Vitamin D Receptor gene problem – Dec 2014 |
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17 Dec, 2014 |
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Acute ischemic stroke 19 percent more likely if even lower vitamin D – Sept 2013 |
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14 Sep, 2013 |