Curr Opin Allergy Clin Immunol. 2012 Apr;12(2):179-85.
Channing Laboratory and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusettes, USA.
PURPOSE OF REVIEW: Over the past 2 years, the number of studies relating vitamin D deficiency and asthma and allergies has increased significantly. The purpose of this review is to update the last review in this journal and examine the evidence of the relationship between vitamin D deficiency and childhood asthma and allergies.
RECENT FINDINGS: In the past 2 years since the last review, there have been many studies, both cross-sectional and prospective, that have investigated the effects of vitamin D on the inception and severity of asthma and allergies.
Most, but not all, studies have shown that low vitamin D levels increase the risk for asthma and allergies, but a few suggest an increased risk with high levels. Results from small trials of short duration suggest that vitamin D supplementation decreases severity of eczema and decreases the risk for asthma exacerbations.
SUMMARY: Data that vitamin D deficiency results in increased risks for asthma and allergies continues to accumulate. However, the optimal level of vitamin D that decreases both the risk for development and severity of these disorders remains elusive. Results of ongoing clinical trials of vitamin D supplementation will be needed before recommendations can be firmly established.
- Hypothesis adolescent allergies associated with low vitamin D levels
- Overview Asthma and Vitamin D
- Asthma associated with low vitamin D, independent of allergic status – Nov 2015
The items in Autoimmune and Infant-Child D are listed here:
- Breastfeeding a child without adding vitamin D increases risk of many food allergies (egg whites in this case) – Jan 2020
- Antibiotics increased the risk of asthma by 47%, and allergies by 25% - Dec 2019
- Low vitamin D newborns getting cows milk formula more likely to get allergies – RCT Oct 2019
- Childhood allergies (Atopy) 4.8 X more likely if low vitamin D in early pregnancy – Aug 2019
- Kawasaki disease (strawberry tongue) not treated by occasional 400 IU of Vitamin D – Feb 2019
- Food allergy is linked to season of birth, sun exposure, and vitamin D deficiency – Jan 2019
- Childhood Food Allergies (UK 1 in 14) – huge recent increase (low vitamin D) - Dec 2018
- Food allergies are associated with Vitamin D thru genes, etc. – March 2018
- Food allergies in children may be due to earlier low Vitamin D, Omega-3 and Zinc – Aug 2017
- T1 Diabetes associated with many other autoimmune diseases (all related to low vitamin D) – May 2017
- Infant allergy to cow’s milk will go away if have high levels of vitamin D – Jan 2017
- Food allergies and low vitamin D – thymus may be the connection – June 2016
- Food allergies 6 times higher in South Australia - 2009
- Hypothesis – Australia has highest rate of food allergy due to avoiding the sun – Sept 2015
- Food allergy 12X more likely if low vitamin D and vitamin D binding gene problem – Aug 2015
- Too much vitamin D: 1 pcnt increase in infants with food allergy, too little: 500 pcnt increase in children with food allergy - Aug 2015
- Kawasaki disease (strawberry tongue) associated with very low vitamin D – May 2015
- Less sun (less vitamin D) more anaphylaxis (severe allergic reaction) – June 2014
- Low vitamin D at birth associated with later milk sensitization, allergic rhinitis and asthma – Nov 2014
- Pink eye (seasonal allergic conjunctivitis) associated with low vitamin D and high vitamin E – March 2014
- 11X more non-immigrant children allergic to peanuts if vitamin D less than 20 ng – Feb 2013
- 30 to 40 ng of vitamin D associated with the least peanut allergy – Nov 2012
- High level of maternal vitamin D and infant food allergy – controversy
- Youths with autoimmunity disorders were 2.3 X more likely to be vitamin D deficient – July 2012
- Still unsure of association between vitamin D and asthma and allergies – review April 2012
- Allergy - Overview
- 3X more allergy to peanuts if child born with low UV – Feb 2011
- More childhood allergies when vitamin D is less than 15 ng – Feb 2011