Loading...
 
Translate Register Log In Login with facebookLogin and Register

Snack fortification – Calcium and 30000 IU vitamin D monthly helped – Jan 2011

A pilot randomized controlled trial of oral calcium and vitamin D supplementation using fortified laddoos in underprivileged Indian toddlers.

Eur J Clin Nutr. 2011 Jan 19.
Ekbote VH, Khadilkar AV, Chiplonkar SA, Hanumante NM, Khadilkar VV, Mughal MZ.
Growth and Endocrine Unit, HCJMRI, Jehangir Hospital, Pune, India.

Background/Objectives:Low habitual dietary calcium intake and vitamin D deficiency are common among Indian children. Using 'laddoo', an Indian snack, as a vehicle for administering calcium and vitamin D supplements, a randomized double-blind controlled trial was conducted for 12 months to assess its efficacy on total body less head (TBLH) bone mineral content (BMC) in underprivileged toddlers.Subjects/Methods:A total of 60 toddlers (mean age 2.7±0.52 years, boys=31) were randomized to two groups, (i) study group receiving one calcium fortified laddoo (cereal-legume snack) containing 405?mg calcium per day and (ii) control receiving a non-fortified laddoo, containing 156?mg of indigenous calcium. Both groups also received a laddoo fortified with 30?000?IU of vitamin D(3) per month. Outcome measures included TBLH bone area (BA) and TBLH BMC by GE-Lunar DPX Pro Pencil Beam Dual-Energy X-ray absorptiometry.

Results:At baseline, mean energy, protein and calcium intakes were 71, 72 and 47% of Indian Recommended Dietary allowances. In all, 87 and 83% toddlers were hypocalcaemia and vitamin D deficient, respectively. Mean TBLH BMC was 289.5±45.8?g. Post supplementation, mean TBLH BMC of study group showed a significantly greater (P<0.01) increase of 35% as against 28% in controls and the difference remained significant after adjusting for vitamin D status, calcium intake, height and TBLH BA.

Conclusions:Daily supplementation with calcium fortified laddoo, and monthly vitamin D supplement resulted in a significant increase in TBLH BMC of underprivileged toddlers. We believe that such strategies have the potential of addressing nutritional problems in developing countries.European Journal of Clinical Nutrition doi:10.1038/ejcn.2010.288. PMID: 21245882
– – – – – –

30,000 IU monthly = only about 1,000 IU daily

Institute of Medicine Nov 2010 said 600 IU to 2500 IU at this age

Graph of RDA and Upper Limit

See any problem with this page? Report it (FINALLY WORKS)