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Seniors with more than 20 ng of vitamin D were 14 percent stronger – May 2011

Effect of Vitamin D Nutritional Status on Muscle Function and Strength in Healthy Women Aged over Sixty-Five Years.

J Nutr Health Aging. 2011;15(5):349-54.
Mastaglia SR, Seijo M, Muzio D, Somoza J, Nuñez M, Oliveri B.
S.R. Mastaglia, Av. Cordoba 2351(1120), Tel/Fax: 541159508972, Buenos Aires- Argentina, Silvinamastaglia at hotmail.com.

Background: Vitamin D insufficiency is common in elderly adults, and leads to secondary hyperparathyroidism, bone loss, muscle weakness, and osteoporotic fractures.

Objective: To evaluate the relation between vitamin D nutritional status and muscle function and muscle strength in women aged over 65 years.

Methods: Fifty-four postmenopausal women from Buenos Aires (latitude 34° S), average age (X±DS) 71±4, were included in the study. Determinations of serum calcium, phosphate, 25 hydroxyvitamin D (25OHD), intact parathormone (iPTH) and calciuria / creatininuria ratio in 24-hour urine samples were performed. Muscle function was assessed by means of walking-speed test, standing balance, and sit-to-stand tests. Lower extremity muscle strength was determined using a manual dynamometer.

Results: 25OHD levels ?20ng/ml were found to be associated with better lower extremity muscle function and strength. Forty- six % of participants had 25OHD levels ?20ng/ml. Women with 25OHD levels ?20ng/ml scored higher on the

  • muscle function tests (11.2±0.9 vs.10.0±2.1; p<0.003) and had stronger
  • knee extensor (13.4±2.7 vs.11.6±2.5 Kg.; p<0.03) and
  • hip abductor (8.3±2.7 vs. 7.3±3.1 Kg; p<0.04) muscles;

strength of their hip flexors tended to be higher but did not reach significantly different values (17.0±3.3 vs. 15.4±2.8 Kg.; 0.1>p>0.05). Negative correlation was observed between iPTH and muscle function (r= -0.436; p<0.02).

Conclusion: 25OHD levels ?20ng/ml are needed for a better muscle function and strength. Assessing vitamin D nutritional status in adults aged ? 65 years would allow correcting hypovitaminosis D and improve muscle function and strength.

PMID: 21528160
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When > 20 ng of vitamin D: Strength increase: Muscle 12%, knee 16%, hip 14%
Wonder how much stronger if > 30 ng, >40 ng, etc.

See also VitaminDWiki