Risk of Autoimmune Uveitis (an outer eye inflammation) decreases 6% for each 1 ng higher level of vitamin D – Coimbra July 2024

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Serum Vitamin D Levels as Biomarkers in Patients with Autoimmune Uveitis and their Possible Correlation with Disease Activity

Ocul Immunol Inflamm. 2024 Jul;32(5):628-635. doi: 10.1080/09273948.2023.2184699 PDF behind paywall
Karine Koller 1, Kimble Matos Teixeira Fonseca 1, Kelsy N Areco 2, Yuslay Fernández-Zamora 1, Luci Meire Pereira Silva 1, Ricardo Pedro Casaroli-Marano 1 3, Cicero Galli Coimbra 4, Cristina Muccioli 1

This study investigated the correlation between serum vitamin D levels and intraocular inflammation in patients with autoimmune uveitis (AIU). We evaluated 67 patients with active and inactive AIU and measured their serum 25-hydroxyvitamin D 25(OH)D concentration, sun exposure habits, number of relapses, and complications. Of the patients evaluated, 85% had significantly lower vitamin D levels, and patients with active uveitis had lower 25(OH)D levels than those with inactive uveitis.

The odds of developing active uveitis decreased by 6% with each 1-unit increase in 25(OH)D. Patients with recurrent active AIU had significantly lower 25(OH)D serum levels than inactive forms, indicating that low vitamin D levels may alter the clinical course of intraocular inflammation in AIU. Additionally, the study found that a higher mean BMI increased the chances of an individual having active uveitis by 14%. These results suggest that serum vitamin D concentration could be a prognostic clinical biomarker in AIU.

From the web

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5+ VitaminDWiki pages have UVEITIS in the title

The list is automatically updated

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VitaminDWiki – Vision category contains:

• 12% larger pupils in children who are Vitamin D deficient – Feb 2024 parasympathetic nervous system?
• Myopia, AMD, Dry Eye, and Diabetic Retinopathy are all associated with low Vitamin D - April 2023
• An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022
• Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1 – Nov 2019
• Vitamin D treats and prevents a variety of eye problems (need 70 ng) – June 2018
• Vitamin D and Myopia, AMD, Diabetic Retinopathy, Uveitis, Glaucoma, VDR etc. – May 2015
• Tears often have 25 % higher levels of vitamin D than does blood

Vision problems having many studies on VitaminDWiki

• Uveitis (inflamed eye) and Vitamin D - many studies
• Age-Related Macular Degeneration and Vitamin D - many studies
• Cataracts and Vitamin D - many studies
• Diabetic Retinopathy associated with low Vitamin D - many studies
• 7+ studies of Glaucoma and Vitamin D
• Dry Eyes treated by Omega-3 and Vitamin D – many studies
• 21+ studies of Myopia and Vitamin D

113 items in Vision category

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VitaminDWiki – Autoimmune category contains

• 206 items in Autoimmune category
• Vitamin D and   MS    Asthma    RA    Diabetes    Gut   Allergy    Hay Fever    Lupus    Psoriasis
• Predicted 95% autoimmune cured by HIGH-DOSE vitamin D - 2014
• 10% of the UK have Autoimmune Diseases - Lancet May 2023 PDF is behind a paywall
  • Increase in 20 years : coeliac disease 2.19 X. Sjogren's syndrome 2.09, and Graves' disease 2.07
  • All 43 references are FREE on-line
• Autoimmune diseases fought by Vitamin D, especially if have more than 40 ng – Sept 2022
• The BEST Nutrient for Autoimmune Conditions (Vitamin D) - video May 2022
• The number 1 Deficiency behind All Autoimmune Diseases (Vitamin D) video - Dec 2023
• Autoimmune disease clusters run in families having low D
• How Vitamin D reduces inflammation, improves immunity and fights autoimmunity – review Dec 2018
• 120 doctors and 20,000 MS patients using high dose Vitamin D Dec 2018
• Vitamin D has treated Multiple Sclerosis and autoimmune diseases for 16 years – Coimbra April 2018
• Vitamin D Receptor is associated in over 58 autoimmune studies
• More autoimmune disease if higher pollution or lower UVB - Feb 2023
• Many autoimmune diseases associated with low vitamin D or poor Vit D genes – July 2019
  

See also web: consensus that ~50 diseases are autoimmune, ~50 more are suspected:

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VitaminDWiki - 2 studies in both categories Vision and Autoimmune

This list is automatically updated

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VitaminDwiki - Coimbra high-dose vitamin D protocol - many studies

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2 of the many related items on the web

• Vitamin D deficiency and non-infectious uveitis: A systematic review and Meta-analysis - Feb 2024 FREE PDF
• The association between vitamin D and uveitis: A comprehensive review, March 2022, Pages 321-330 https://doi.org/10.1016/j.survophthal.2021.07.006