International Journal of Cancer, https://doi.org/10.1002/ijc.32105
Fie Juhl Vojdeman PhD Christian Medom Madsen MD Kirsten Frederiksen PhD Darshana Durup PhD Anja Olsen PhD Louise Hansen PhD …
Wonder why a few cancers show increased rates with higher levels of vitamin D
They excluded those people who already had (some form of) Cancer.
Is this exclusion a clue?
Cancer category starts with the following
181 items Overview Cancer and vitamin D
- After Cancer Diagnosis
- Bladder Cancer
- Breast Cancer
199 items Overview Breast Cancer and Vitamin D
- Colon Cancer
94 items Overview Cancer-Colon and vitamin D
- Lung Cancer
39 items Overview Lung cancer and vitamin D
- Lymphoma Cancer
- Other Cancer
- Prostate Cancer
81 items Prostate Cancer and Vitamin D studies
- Pancreatic Cancer
- Skin Cancer
100 items Overview Suntans melanoma and vitamin D
- Evidence that Vitamin D prevents Cancer – Grant Feb 2018
- Cancer risk in older women reduced 32 percent by 2,000 IU of Vitamin D plus Calcium – 4 year RCT Oct 2016
- Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
- Breast Cancer Mortality reduced 60 percent if more than 60 ng of Vitamin D – meta-analysis June 2017
- Diagnosed with breast cancer – take vitamin D to cut chance of death by half – July 2018
- Pancreatic cancer 55 percent less likely if optimal vitamin D (vs low) – Nov 2017
- Melanoma 25 X more likely if low vitamin D – Feb 2018
- Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014
- Cancer treatment by Vitamin D sometimes is restricted by genes – Oct 2018
- Risk of Cancer increased due to Vitamin D Receptor – meta-analysis of 73 studies Jan 2016
- Cancer not treated by Vitamin D when ignore dose size, type, and length of trial – meta-analysis April 2018
The following charts are probably for
Melanoma, Non-melanoma, Prostate, Hematological, Non-Hodgkin, Lymphoma, Lung
(the figures in the submitted PDF was not clearly labeled)
Vitamin D has been linked to cancer development in both pre‐clinical and epidemiological studies. This study examines the association between serum levels of vitamin D and cancer incidence in the Capital Region of Denmark. Individuals who had vitamin D analyzed at The Copenhagen General Practitioners Laboratory between April 2004 and January 2010 were linked to Danish registries with end of follow‐up date at Dec 31st 2014, excluding individuals with pre‐existing cancer. Cox regression models adjusted for age in one‐year intervals, sex, month of sampling, and Charlson Comorbidity Index were applied. The study population of 217,244 individuals had a median vitamin D level of 46 nmol/L (IQR 27‐67 nmol/L).
Non‐melanoma skin cancer was the most frequent form of cancer, followed by breast‐, lung‐, and prostate cancers.
No associations were found between increments of 10nmol/L vitamin D and incidence of breast, colorectal, urinary, ovary or corpus uteri cancer.
However, higher levels of vitamin D were associated with higher incidence of
- non‐melanoma (HR 1.09 [1.09‐1.1]) and
- melanoma skin cancer (HR 1.1 [1.08‐1.13]) as well as
- prostate (HR 1.05 [1.03‐1.07]) and
- hematological cancers (HR 1.03 [1.01‐1.06]),
but with lower incidence of
- lung cancer (HR 0.95 [0.93‐0.97]).
In this study, vitamin D levels are not associated with the incidence of several major cancer types, but higher levels are significantly associated with a higher incidence of skin, prostate, and hematological cancers as well as a lower incidence of lung cancer. These results do not support an overall protective effect against cancer by vitamin D.
123 visitors, last modified 08 Jan, 2019, URL:
- After Cancer Diagnosis