Loading...
 
Toggle Health Problems and D

Prevention and Treatment of Vitamin D Deficiency – Nov 2012

Calcif Tissue Int. 2012 Nov 3.
Sinha A, Cheetham TD, Pearce SH.
Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.

Vitamin D insufficiency and deficiency are widespread in many countries. We review the evidence pertaining to its prevention and treatment. Deficiency may be adequately treated with many different therapeutic regimens of either cholecalciferol or ergocalciferol, owing to the high therapeutic index of both compounds. Nevertheless, the current evidence suggests that regular dosing with oral cholecalciferol (e.g., 60,000 IU weekly) may have slight advantages over other regimens when replenishing vitamin D stores following deficiency. For long-term supplementation, smaller regular doses, such as cholecalciferol 1,000 IU daily, or 10,000 IU weekly, are suitable. Giving reliable and specific advice about appropriate sunlight exposure remains difficult because of differing interindividual skin pigmentation and variable sunlight UVB content at different latitudes, at different times of year, and in different terrestrial environments.

PMID: 23124916

PDF is attached at the bottom of this page
PDF was public domain in Dec 2012

Attached files

ID Name Comment Uploaded Size Downloads
1889 Prevention and Treatment of Vitamin D Deficiency.pdf admin 28 Dec, 2012 251.42 Kb 901