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Preeclampsia and eclampsia associated with lower vitamin D, etc. – Sept 2015

Comparison of Vitamin D levels in cases with preeclampsia, eclampsia and healthy pregnant women

Int J Clin Exp Med 2015;8(9):16280-16286 www.iicem.com /ISSN:1940-5901/IJCEM0011546
Murat Bakacak1, Salih Serin1, Onder Ercan1, Bulent Kostu1, Fazil Avci1, Metin Kiling2, Hakan Kiran1, Gurkan Kiran1
1Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey; 2Department of Biochemistry,School of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey
Received June 17, 2015; Accepted August 5, 2015; Epub September 15, 2015; Published September 30, 2015

The aim of this study is to assess vitamin D levels in eclampsia, preeclampsia and healthy pregnant women and the role of vitamin D deficiency in the etiology of preeclampsia (PE). Forty healthy pregnant women, 83 preeclamptic and 32 eclamptic pregnant women were included. Maternal and infant medical records were reviewed. Blood samples were obtained from all groups. Demographics and serum vitamin D levels were compared between the groups. No statistical differences were observed in age, gravidity, parity, weight, height and BMI between the three groups.

Week of pregnancy and weight at birth in eclamptic and preeclamptic patients were lower compared to the healthy patients (P<0.001 and P<0.001, respectively).

Systolic and diastolic blood pressures were higher in eclamptic (P<0.001) and preeclamptic patients (P<0.001) compared to the healthy pregnant group.

The rate of cesarean section was found to be higher in preeclamptic and eclamptic patients (P<0.001).

Vitamin D levels were lower in both preeclamptic and eclamptic patients compared to healthy normotensive pregnant women (P<0.001).

Preeclamptic and eclamptic women were similar in terms of the data compared. Vitamin D supplementation is considered to decrease the risk of both preeclampsia and eclampsia in the patient population at risk for vitamin D deficiency.


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Attached files

ID Name Comment Uploaded Size Downloads
6157 Preeclampsia T1.jpg admin 13 Nov, 2015 112.28 Kb 2107
6156 Preeclampsia F1.jpg admin 13 Nov, 2015 21.11 Kb 1337
6155 Preeclampsia eclampsia.pdf admin 13 Nov, 2015 292.56 Kb 769