Beneficial Effect of Oligofructose-Enriched Inulin on Vitamin D and E Status in Children with Celiac Disease on a Long-Term Gluten-Free Diet: A Preliminary Randomized, Placebo-Controlled Nutritional Intervention Study.
Nutrients. 2018 Nov 15;10(11). pii: E1768. doi: 10.3390/nu10111768.
Drabińska N1, Krupa-Kozak U2, Abramowicz P3, Jarocka-Cyrta E4.
- Antibiotics, probiotics category has
95 items along with related searches - Prebiotic oligofructose-enriched inulin (Synergy 1) with a Gulten Free Diet increased Vitamin D levels by 42%
- "celiac disease" OR CD 2030 items Jan 2019
- Celiac disease 5.4 times more likely in Northern vs Southern states (vitamin D) – Feb 2017
- Gut bacteria of Crohn's disease patients improved by Vitamin D – March 2018
- Increased Vitamin D not only helps the body, but helps the gut bacteria (perhaps as well as prebiotic)
Items in both categories Children and Gut are listed here:
- Diarrhea and Vitamin D - many studies
- IBD treated in children by Vitamin D, especially if use more than 2,000 IU daily for 12 weeks – meta-analysis – Sept 2022
- Children with Celiac Disease were 2.6X more-likely to be vitamin D deficient – Sept 2020
- Prebiotics increased Vitamin D in celiac disease patients (gut-friendly Vit. D also helps) – RCT Nov 2018
- IBD in children might be associated with low sun exposure
- Inflammatory Bowel Disease in children is associated with low Vitamin D, Iron (also low Zinc for Crohn’s) – Aug 2018
- Crohn's disease in black children is worse in 6 ways – Dec 2015
- Obese children with celiac disease had lower levels of vitamin D – April 2012
Overview Gut and vitamin D contains gut-friendly information
Gut-friendly, Sublingual, injection, topical, UV, sunshineGetting Vitamin D into your blood and cells has the following chart
Getting Vitamin D into your blood and cells also has the following
If poorly functioning gut
Bio-D-Mulsion Forte – especially made for those with poorly functioning guts, or perhaps lacking gallbladder
Sublingual – goes directly into the bloodstream
Fat-soluble Vitamins go thru the slow lymph system
you can make your own sublingual by dissolving Vitamin D in water or use nano form
Oil: 1 drop typically contains 400 IU, 1,000 IU, or 4,000 IU, typically not taste good
Topical – goes directly into the bloodstream. Put oil on your skin, Use Aloe vera cream with Vitamin D, or make your own
Vaginal – goes directly into the bloodstream. Prescription-only?
Bio-Tech might be useful – it is also water-soluble
Vitamin D sprayed inside cheeks (buccal spray) - several studies
and, those people with malabsorption problems had a larger response to spray
Inject Vitamin D quarterly into muscle, into vein, or perhaps into body cavity if quickly needed
Nanoparticles could be used to increase vitamin D getting to the gut – Oct 2015
Poor guts need different forms of vitamin D has the following
Guesses of Vitamin D response if poor gutBio Form Speed Duration 10 Injection ($$$)
or Calcidiol or CalcitriolD - Slow
C -FastLong 10 Sun/UVB Slow Long 10 Topical
(skin patch/cream, vagina)Slow
Fast nanoNormal 9 Nanoemulsion -mucosal
perhaps activates VDRFast Normal 9? Inhaled (future) Fast Normal 8 Bio-D-Mulsion Forte Normal Normal 6 Water soluble (Bio-Tech) Normal Normal 4 Sublingual/spray
(some goes into gut)Fast Normal 3 Coconut oil based Slow Normal 2 Food (salmon etc.) Slow Normal 2 Olive oil based (majority) Slow Normal 10= best bioavailable, 0 = worst, guesses have a range of +-2
Speed: Fast ~2-6 hours, Slow ~10-30 hours
Duration: Long ~3-6 months, Normal = ~2 monthsDownload the PDF from VitaminDWiki
Prebiotics have been shown to improve absorption of some nutrients, including vitamins. This pilot study evaluated the effect of the prebiotic oligofructose-enriched inulin (Synergy 1) on fat-soluble vitamins status, parathormone, and calcium-related elements in pediatric celiac disease (CD) patients (n = 34) on a strict gluten-free diet (GFD). Participants were randomized into a group receiving 10 g of Synergy 1 or placebo (maltodextrin) together with a GFD. At baseline and after 3 months of intervention, 25-hydroxyvitamin D [25(OH)D], parathormone, vitamin E and A, calcium, phosphate, magnesium, total protein, and albumin were determined. Concentration of 25(OH)D increased significantly (p < 0.05) by 42% in CD patients receiving Synergy 1 in GFD, whereas no change was observed in placebo. Vitamin D status reached an optimal level in 46% of patients receiving Synergy 1. No significant difference in parathormone, calcium, and phosphate levels was observed. Concentration of vitamin E increased significantly (p < 0.05) by 19% in patients receiving Synergy 1, but not in the placebo. Vitamin A levels were not changed.
Supplementation of GFD with Synergy 1 improved vitamin D and vitamin E status in children and adolescents with CD and could be considered a novel complementary method of management of fat-soluble vitamins deficiency in pediatric CD patients.
Prebiotics increased Vitamin D in celiac disease patients (gut-friendly Vit. D also helps) – RCT Nov 2018Printer Friendly Follow this page for updates8927 visitors, last modified 26 Aug, 2022, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 11273 Preibiotic CD.jpg admin 26 Jan, 2019 20.88 Kb 625 11272 Prebiotics CD.pdf admin 26 Jan, 2019 930.41 Kb 621