Vitamin D in the Prevention and Treatment of Osteoarthritis: From Clinical Interventions to Cellular Evidence.
Nutrients. 2019 Jan 22;11(2). pii: E243. doi: 10.3390/nu11020243.
- Less Knee Osteoarthritis if take more Vitamin D – 8 MRI confirmations – Nov 2018
- Knee Osteoarthritis benefited by 20 ng of Vitamin D for 5 years – RCT July 2018
- Knee osteoarthritis helped by vitamin D2 (40,000 IU weekly raised 57 % above 30 ng) June 2017
- Reduced knee osteoarthritis if consistently supplement with vitamin D for 2 years – April 2017
- Knee Osteoarthritis (Radiographic ) 3X less if have lots of Magnesium – May 2015
- Knee pain in seniors predicted by low vitamin D 5 years before – Feb 2014
Osteoarthritis category includes the following
Overview Osteoarthritis and Vitamin D
Search VitaminDWiki for CARTILAGE 393 items as of July 2018
See also Ankylosing spondylitis
Search VitaminDWiki for "Knee Osteoarthritis" 263 items as of April 2018
Older adults are recommended vitamin D to prevent fractures. Though this population is also at risk of osteoarthritis (OA), the effect of vitamin D on OA is unclear and may differ by disease state. The relationship between vitamin D and OA during OA initiation and progression were considered in this narrative review of in vivo and in vitro studies. Regarding OA initiation in humans, the small number of published observational studies suggest a lack of association between induction of OA and vitamin D status. Most randomized controlled trials were performed in White OA patients with relatively high vitamin D status (>50 nmol/L). These studies found no benefit of vitamin D supplementation on OA progression. However, subset analyses and one randomized controlled pilot trial indicated that vitamin D supplementation may alleviate joint pain in OA patients with low vitamin D status (<50 nmol/L). As the etiology of OA is recently being more fully uncovered, better animal and cell models are needed. According to currently available clinical results, evidence is lacking to set a vitamin D level to prevent OA, and increasing vitamin D status above 50 nmol/L does not seem to benefit OA patients.