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No Hypertension during pregnancy if more than 60 ng of vitamin D – RCT

From Grassroots Health Newsletter March 2017


What effect might vitamin D have on hypertensive disorders during pregnancy?

Data from two clinical trials demonstrate a reduction in hypertensive pregnancy disorders with an increased vitamin D level (Wagner CL et al., Health characteristics and outcomes of two randomized vitamin D supplementation trials during pregnancy: a combined analysis. J Steroid Biochem Mol Biol. 2013 Jul;136:313-20.).

Among 505 pregnant women, there was a 56% reduction in risk of a hypertensive disorder at 40 ng/ml and a 65% risk reduction at 50 ng/ml.

  • 22 participants (4%) were diagnosed with a hypertensive pregnancy disorder; 18 were diagnosed with hypertension and 5 were diagnosed with preeclampsia (1 was diagnosed with both).
  • Among those diagnosed with a hypertensive pregnancy disorder, 73% had final 25(OH)D values below 40 ng/ml.
  • For preeclampsia specifically, all five were below 40 ng/ml.
  • There were no cases of hypertensive disorders among women with vitamin D serum levels above 60 ng/ml.

VDW# = 8330


See also VitaminDWiki

Pages listed in BOTH the categories Pregnancy and Hypertension (preeclampsia)

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