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Neuropathy-Specific Diabetic Quality of Life improved after injection of 600,000 IU of Vitamin D - 2017

Improvement in Neuropathy Specific Quality of Life in Patients with Diabetes after Vitamin D Supplementation

J Diabetes Res. 2017;2017:7928083. doi: 10.1155/2017/7928083. Epub 2017 Dec 28.
Alam U1,2, Fawwad A3,4, Shaheen F3, Tahir B3, Basit A3, Malik RA5,6,7.

VitaminDWiki
Higher quality of life associated with higher levels of vitamin D category listing has 18 items
  • Note: Injection is not required
  • Note: Would probably have even better results if had on-going monthly doses of Vitamin D - perhaps 200,000 IU

Injection contains the following

42 items in Vitamin D Injection category

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  • Injections are currently made by medical professionals into muscle
  • Home injection of Vitamin D appears to be possible in the future
  • Injections are useful for people who might forget to take their periodic supplement (children, elderly, etc) and those who cannot swallow or have poor digestion
  • While Vitamin D2 is historically the common form, Vitamin D3 is far better
  • Should check (if there is time) for possible allergic reaction to Vitamin D or lack of Magnesium for both for loading dose and injection
  • Note 600,000 IU Vitamin D loading dose via capsules is 1/20th the cost($2.40) of an injection, and does not require a prescription
  • 100,000 IU single dose of vitamin D - 2010 has the following
    Image
  • Vitamin D injection lasts longer and has bigger response than weekly oral – Jan 2017 has the following
    Image

 Download the PDF from VitaminDWiki
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Note: Injection lasts about 3 months. Above chart is after 5 months.
Not much Vitamin D left in the body at 5 months

OBJECTIVE: To assess the effect of vitamin D supplementation on neuropathy specific quality of life (NeuroQoL) in patients with painful diabetic neuropathy.

METHODS: This prospective, open label study was conducted between June 2012 and April 2013. Patients with symptomatic diabetic neuropathy were given a single dose of 600,000 IU intramuscular vitamin D, and NeuroQol was assessed at baseline and at five follow-up visits every 4 weeks.

RESULTS: Of 143 participants, 41.3% were vitamin D deficient (vitamin D < 20 ng/ml). Treatment with vitamin D resulted in a significant increase in 25(OH)D (P < 0.0001) and a significant improvement in the NeuroQoL subscale score for emotional distress (P = 0.04), with no significant change in the other NeuroQoL domains of painful symptoms and paresthesia, loss of temperature and touch sensation, unsteadiness, limitation in daily activities, and interpersonal problems. There was a significant reduction in patient perception about foot problems on QoL of "quite a lot" (P < 0.05) and "very much" (P < 0.0001) with a significant reduction in the baseline response of having a "poor" QoL from 5.2% to 0.7% (P < 0.0001) and an increase in the response of an "excellent QoL" from 1.5% to 7.4% (P < 0.0001).

CONCLUSION: Vitamin D is effective in improving quality of life in patients with painful diabetic neuropathy.

PMID: 29445752 PMCID: PMC5763097 DOI: 10.1155/2017/7928083

Created by admin. Last Modification: Sunday April 29, 2018 09:29:13 UTC by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
9545 NeuroQoL.jpg admin 18 Mar, 2018 15:48 19.34 Kb 43
9544 Neuropathy QoL.pdf PDF 2017 admin 18 Mar, 2018 15:48 700.65 Kb 82
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