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More survive Breast Cancer if more vitamin D – 2X fewer deaths with just 30 ng -meta-analysis March 2014

Meta-analysis of Vitamin D Sufficiency for Improving Survival of Patients with Breast Cancer

Anticancer Research March 2014 vol. 34 no. 3 1163-1166
SHARIF B. MOHR 1⇑, EDWARD D. GORHAM 1,2, JUNE KIM 1, HEATHER HOFFLICH 2 and CEDRIC F. GARLAND 1,2
1 Scientific Programs Office, Code 01A, Naval Health Research Center, San Diego, CA, U.S.A.
2 Department of Family and Preventive Medicine 0620, University of California, San Diego, La Jolla, CA, U.S.A.
Correspondence to: Sharif Mohr, Scientific Programs Office, Code 01A, Naval Health Research Center, San Diego, CA 92106, U.S.A. sbmohr75 at gmail.com

Background/Aim: To determine whether higher serum 25-hydroxyvitamin D [25(OH)D] at diagnosis is associated with longer survival of patients with breast cancer.

Materials and Methods: A meta-analysis was performed of five studies of the relationship between 25(OH)D and mortality from breast cancer. A pooled hazard ratio was calculated using a random-effects model. The Der Simonian-Laird test was used to assess homogeneity.

Results: Higher serum concentrations of 25(OH)D were associated with lower case-fatality rates after diagnosis of breast cancer. Specifically, patients in the highest quintile of 25(OH)D had approximately half the death rate from breast cancer as those in the lowest.

Conclusion: High serum 25(OH)D was associated with lower mortality from breast cancer. Serum 25(OH)D in all patients with breast cancer should be restored to the normal range (30-80 ng/ml), with appropriate monitoring. Clinical or field studies should be initiated to confirm that this association was not due to reverse causation.



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PDF is attached at the bottom of this page

Studies in all 3 categories: Breast Cancer, Meta-analysis and Mortality


derived from Grassroots 2013

All Breast Cancer Meta-analysis studies in VitaminDWiki

Studies in all 3 categories: Cancer, Meta-analysis and Mortality

Attached files

ID Name Comment Uploaded Size Downloads
3891 Breast Cancer Survival F4.jpg admin 08 May, 2014 20:30 31.33 Kb 696
3890 Breast Cancer survival F3.jpg admin 08 May, 2014 20:29 19.97 Kb 756
3674 Breast Cancer meta-analysis.pdf PDF 2014 admin 06 Mar, 2014 13:24 109.60 Kb 547
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