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Metabolic Syndrome associated with low vitamin D in abdominal obese women – Jan 2019

Relationships between Vitamin D3 and Metabolic Syndrome

Int. J. Environ. Res. Public Health 2019, 16(2), 175; https://doi.org/10.3390/ijerph16020175
Sylwia Wieder-Huszla 1, Anna Jurczak 1, Małgorzata Szkup 2, Katarzyna Barczak 3, Barbara Dołęgowska 4, Daria Schneider-Matyka 2, Joanna Owsianowska 1 and Elżbieta Grochans 2,

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The growing number of overweight and obese individuals is an alarming global problem; these conditions are risk factors for the development of health problems such as metabolic syndrome (MetS), type-2 diabetes, atherosclerosis, and cardiovascular disease. Numerous studies have suggested that vitamin D3 deficiency plays a role in the pathogenesis of MetS. The aim of this study was to analyze the relationship between MetS and vitamin D3 levels in women. Laboratory analysis demonstrated that only 26.89% of the participants had vitamin D3 levels close to normal, and waist-to-hip ratio (WHR) measurements revealed android obesity in 75.63% of the women. The menstruating women more often suffered from vitamin D3 deficiency, and less often had elevated vitamin D3 levels.
The conclusions are as follows: (1) There were no statistically significant relationships between vitamin D3 levels and MetS parameters, namely the level of triglycerides, the levels of low- and high-density lipoproteins (LDL and HDL), the level of total cholesterol, and systolic and diastolic blood pressure (SBP and DBP).
Vitamin D deficiency was only observed in the women with abdominal obesity. (2) Low vitamin D3 levels were typical of perimenopausal women. Age was a variable correlating with vitamin D. (3) The presence of menstrual cycles was an important contributor to vitamin D levels. Vitamin D deficiency was significantly more common in the menstruating women.


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11182 Metabolic Syndrome.pdf admin 09 Jan, 2019 290.65 Kb 588