Immune Modulatory Effects of Vitamin D on Viral Infections
Nutrients 2020, 12(9), 2879; https://doi.org/10.3390/nu12092879
by Maheen Siddiqui 1,†,Judhell S. Manansala 1,†,Hana A. Abdulrahman 2,Gheyath K.
Nasrallah 1,2OrcID,Maria K. Smatti 2OrcID,Nadin Younes 1,2,Asmaa A. Althani 1,2 andHadi M. Yassine 1,2,*OrcID
1 College of Health Science-QU Health, Qatar University, Doha 2713, Qatar
2 Biomedical Research Center, Qatar University, Doha 2713, Qatar
- Overview HIV and vitamin D
- Colds and flu prevented and treated by Vitamin D - many studies
- Respiratory infections reduced by 63 percent with 4000 IU vitamin D daily - RCT Dec 2012
- Hepatitis B virus and Vitamin D - many studies
- Vitamin D prevents Hepatitis-C and helps treat it (many studies)
- Overview Influenza and vitamin D
Virus category starts with the following
see also
Immunity, Ebola, HIV, Influenza Hepatitis B Hepatitis-C,Rotavirus, Shingles Enveloped Virus Virus-Pregnancy category has
Many viruses can apparently be dealt with by:
- Vaccination (if avaiable & affordable and person is willing to have the side-effects - which can include death)
- Getting Vitamin D into your blood
- Increasing the vitamin D actually getting to cells Magnesium, Omega-3, Resveratrol, etc
Especially enveloped viruses", Herpes, Zoster, Epstein, Hepatitis, Ebola, Dengue, Yellow fever, Measles, Mumps, smallpox
COVID-19 treated by Vitamin D - studies, reports, videos as of Sept 17 included
- 32 trial registrations, 1 trial result, 19 observations, 9 recommendations, 42 associations, 68 speculations, 23 videos
- and now has the following recent updates
Top Vitamin D and COVID-19 recent updates
- COVID-19 2.7 X more likely to be severe if less than 30 ng of vitamin D (China) – Jan 2021
- 2.7 fewer COVID-19 hospital deaths in those having more than 30 ng of vitamin D – Mayo Jan 9, 2021
- Vitamin D Help Us Fight Infections - interview of Dr. Thakkar (transcript) Jan 20, 2021
- COVID-19 onset strongly associated with latitude in Europe (Vitamin D)– Jan 21, 2021
- France: 73 experts and 6 academies recommend vitamin D to prevent COVID-19 Jan 19, 2021
- Elderly COVID-19 patients getting 400,000 IU of vitamin D had better survival (Italy, April)– Jan 14, 2021
- Vitamin D-COVID interview by Dr. Campbell of Davies (member of UK Parliament) - Jan 17, 2021
- Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
- Many COVID-19 risks are associated with low vitamin D (7 studies) – Systematic Review Jan 2021
- 40 ng of Vitamin D to fight COVID 15K to 50K weekly or 100K monthly - Spanish Jan 2021
- Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
- Unraveling the roles of vitamin D status and melanin during COVID-19 (Review) Jan 11
- 30 x fewer COVID-19 deaths in those getting 400,000 IU of Vitamin D - Jan 2021
- 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
- 3.7 X less likely to die of COVID-19 if supplemented with Vitamin D - meta-analysis Jan 5, 2021
- COVID-19 test positive 4.5 X more likely if had low vitamin D test within 4 years – Jan 6, 2021
- Don’t Let COVID-19 Patients Die With Vitamin D Deficiency - Jan 5, 2021
- Less likely to test positive for COVID-19 if higher Vitamin D – meta-analysis Jan 6, 2021
- Vitamin D reduces COVID-19 by 80 percent - anonymous meta-analysis - Jan 5, 2021
- COVID 19 Video - Drs. Seheult and Campbell : Lessons Learned and a Look Ahead - Jan 4
- Many drugs increase ACE2 and COVID-19 (176 page review) - Dec 2020
- Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
- Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination by VItaminDWiki
- COVID-19 lung infection upsets Vitamin D genes (so more or different form of Vit D is required) - Dec 22, 2020
- COVID-19 Disease and Vitamin D: A Mini-Review – Dec 15, 2020
- French Consensus – 200,000 IU of Vitamin D if get COVID-19 – Dec 22, 2020
- Rational approach to COVID-19: 50k-100k of Vitamin D weekly – Dec 2020
- Shift workers 2X more likely to get COVID-19 (low Vitamin D) - Dec 2020
- COVID-19 plus pneumonia in ICU with low vitamin D equaled Death - Dec 2020
- Excellent on-going analysis of Vitamin D and COVID-19 publications
- 7X less likely to die of COVID-19 if taking Vitamin D loading dose – Dec 11, 2020
- COVID-19 patients with low vitamin D had far fewer natural killer cells – Dec 2020
- COVID-19 Vitamin D: Overview of Evidence by Dr. Seheult (Video and transcript) - Dec 10, 2020
- 75 articles indicate that Vitamin D should fight COVID-19 – Evidence Review Dec 10, 2020
- COVID-19 Vitamin D: Overview by Dr. in Sri Lanka (Video and transcript) - Dec 8, 2020
- Vitamin D recommended to fight COVID-19 by 2 groups – Dec 7, 2020
- Vitamin D helps athletes while reducing their COVID-19 risk - Dec 4, 2020
- 5X more likely to test positive for COVID-19 if low vitamin D in previous 5 years (900,000 people) - Dec 4, 2020
- 5.8 X more likely to die of COVID-19 if low vitamin D - Systematic Review Dec 3, 2020
- Evidence of Vitamin D fighting COVID-19 etc. - take 4,000 IU if less than 20 ng (UK) – Dec 1, 2020
- 3.8 X higher risk of COVID-19 death if low vitamin D – Belgium Nov 25, 2020
- Hyperglycemic 2X more likely to have severe COVID-19 - Nov 2020 Diabetes
- COVID-19 protocol proposed in India includes Vitamin D - Nov 12, 2020
- A Medical School COVID-19 protocol includes Vitamin D for all phases – Marik Nov 2020
- Vitamin D has eliminated ICU COVID-19 in hospital in Dubai since June - Sept 26, 2020
- COVID-19 and Vitamin D: Health Authorities do not understand risk-reward – Nov 2020
- c19study.com/d has excellent synopsis of Vitamin D and COVID studies
-
click to see 3 weeks in Nov 2020
-
- COVID-19 – Putative Roles of Vitamin D – Nov 2020
- Fight COVID-19 without drugs or vaccines, Vitamin D is the single most-studied way – Nov 2020
- Hospital COVID-19 observation: 7X more likely to live if more than 20 ng of vitamin D– Nov 19, 2020
- Higher vitamin D associated with fewer cases and deaths in India Nov 2020
- COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020
- 2X fewer COVID-19 deaths observed if infrequent vitamin D (2X more deaths if daily dose) – ClinicalTrial Oct 20, 2020
- Vitamin D and COVID-19 - observational studies found it helps, never hurts - Campbell Oct 31, 2020
- COVID-19 patients who happened to be taking Vitamin D did much better – Oct 27,2020
- 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020
- Virtually no COVID-19 cases in countries having more than 30 ng of Vitamin D - Sept 17, 2020
- Rate of COVID-19 test positive is 40 pcnt lower if high vitamin D (192,000 people) - Holick Sept 2020
Download the PDF from VitaminDWiki
Viral infections have been a cause of mortality for several centuries and continue to endanger the lives of many, specifically of the younger population. Vitamin D has long been recognized as a crucial element to the skeletal system in the human body. Recent evidence has indicated that vitamin D also plays an essential role in the immune response against viral infections and suggested that vitamin D deficiency increases susceptibility to viral infections as well as the risk of recurrent infections.
For instance, low serum vitamin D levels were linked to increased occurrence of high burdens viral diseases such as hepatitis, influenza, Covid-19, and AIDS. As immune cells in infected patients are responsive to the ameliorative effects of vitamin D, the beneficial effects of supplementing vitamin D-deficient individuals with an infectious disease may extend beyond the impact on bone and calcium homeostasis. Even though numerous studies have highlighted the effect of vitamin D on the immune cells, vitamin D’s antiviral mechanism has not been fully established. This paper reviews the recent mechanisms by which vitamin D regulates the immune system, both innate and adaptive systems, and reflects on the link between serum vitamin D levels and viral infections.
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